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Avian Influenza (H5N1) Virus of Clade 2.3.2 in Domestic Poultry in India

Overview of attention for article published in PLOS ONE, February 2012
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (90th percentile)
  • High Attention Score compared to outputs of the same age and source (86th percentile)

Mentioned by

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1 news outlet
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1 X user

Citations

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56 Dimensions

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61 Mendeley
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Title
Avian Influenza (H5N1) Virus of Clade 2.3.2 in Domestic Poultry in India
Published in
PLOS ONE, February 2012
DOI 10.1371/journal.pone.0031844
Pubmed ID
Authors

Shanmuga Nagarajan, Chakradhar Tosh, David K. Smith, Joseph Sriyal Malik Peiris, Harshad Vinayakrao Murugkar, Rajangam Sridevi, Manoj Kumar, Megha Katare, Rajlaxmi Jain, Zohra Syed, Padmanava Behera, Chung L. Cheung, Rekha Khandia, Sushil Tripathi, Yi Guan, Shiv Chandra Dubey

Abstract

South Asia has experienced regular outbreaks of H5N1 avian influenza virus since its first detection in India and Pakistan in February, 2006. Till 2009, the outbreaks in this region were due to clade 2.2 H5N1 virus. In 2010, Nepal reported the first outbreak of clade 2.3.2 virus in South Asia. In February 2011, two outbreaks of H5N1 virus were reported in the State of Tripura in India. The antigenic and genetic analyses of seven H5N1 viruses isolated during these outbreaks were carried out. Antigenic analysis confirmed 64 to 256-fold reduction in cross reactivity compared with clade 2.2 viruses. The intravenous pathogenicity index of the isolates ranged from 2.80-2.95 indicating high pathogenicity to chickens. Sequencing of all the eight gene-segments of seven H5N1 viruses isolated in these outbreaks was carried out. The predicted amino acid sequence analysis revealed high pathogenicity to chickens and susceptibility to the antivirals, amantadine and oseltamivir. Phylogenetic analyses indicated that these viruses belong to clade 2.3.2.1 and were distinct to the clade 2.3.2.1 viruses isolated in Nepal. Identification of new clade 2.3.2 H5N1 viruses in South Asia is reminiscent of the introduction of clade 2.2 viruses in this region in 2006/7. It is now important to monitor whether the clade 2.3.2.1 is replacing clade 2.2 in this region or co-circulating with it. Continued co-circulation of various subclades of the H5N1 virus which are more adapted to land based poultry in a highly populated region such as South Asia increases the risk of evolution of pandemic H5N1 strains.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 61 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Indonesia 2 3%
Denmark 1 2%
Bangladesh 1 2%
Unknown 57 93%

Demographic breakdown

Readers by professional status Count As %
Researcher 12 20%
Student > Ph. D. Student 11 18%
Student > Master 6 10%
Professor 5 8%
Student > Bachelor 5 8%
Other 14 23%
Unknown 8 13%
Readers by discipline Count As %
Agricultural and Biological Sciences 21 34%
Medicine and Dentistry 8 13%
Veterinary Science and Veterinary Medicine 6 10%
Immunology and Microbiology 4 7%
Biochemistry, Genetics and Molecular Biology 3 5%
Other 12 20%
Unknown 7 11%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 13. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 May 2020.
All research outputs
#2,358,399
of 22,691,736 outputs
Outputs from PLOS ONE
#30,083
of 193,720 outputs
Outputs of similar age
#14,662
of 156,609 outputs
Outputs of similar age from PLOS ONE
#465
of 3,532 outputs
Altmetric has tracked 22,691,736 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 193,720 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.0. This one has done well, scoring higher than 84% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 156,609 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 3,532 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 86% of its contemporaries.