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Identification and bioactive potential of endophytic fungi isolated from selected plants of the Western Himalayas

Overview of attention for article published in SpringerPlus, January 2013
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (73rd percentile)
  • High Attention Score compared to outputs of the same age and source (89th percentile)

Mentioned by

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1 X user
facebook
1 Facebook page
wikipedia
1 Wikipedia page

Citations

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106 Dimensions

Readers on

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217 Mendeley
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Title
Identification and bioactive potential of endophytic fungi isolated from selected plants of the Western Himalayas
Published in
SpringerPlus, January 2013
DOI 10.1186/2193-1801-2-8
Pubmed ID
Authors

Masroor Qadri, Sarojini Johri, Bhahwal A Shah, Anamika Khajuria, Tabasum Sidiq, Surrinder K Lattoo, Malik Z Abdin, Syed Riyaz-Ul-Hassan

Abstract

This study was conducted to characterize and explore the endophytic fungi of selected plants from the Western Himalayas for their bioactive potential. A total of 72 strains of endophytic fungi were isolated and characterized morphologically as well as on the basis of ITS1-5.8S-ITS2 ribosomal gene sequence acquisition and analyses. The fungi represented 27 genera of which two belonged to Basidiomycota, each representing a single isolate, while the rest of the isolates comprised of Ascomycetous fungi. Among the isolated strains, ten isolates could not be assigned to a genus as they displayed a maximum sequence similarity of 95% or less with taxonomically characterized organisms. Among the host plants, the conifers, Cedrus deodara, Pinus roxburgii and Abies pindrow harbored the most diverse fungi, belonging to 13 different genera, which represented almost half of the total genera isolated. Several extracts prepared from the fermented broth of these fungi demonstrated strong bioactivity against E. coli and S. aureus with the lowest IC(50) of 18 μg/ml obtained with the extract of Trichophaea abundans inhabiting Pinus sp. In comparison, extracts from only three endophytes were significantly inhibitory to Candida albicans, an important fungal pathogen. Further, 24 endophytes inhibited three or more phytopathogens by at least 50% in co-culture, among a panel of seven test organisms. Extracts from 17 fungi possessed immuno-modulatory activities with five of them showing significant immune suppression as demonstrated by the in vitro lymphocyte proliferation assay. This study is an important step towards tapping the endophytic fungal diversity from the Western Himalayas and assessing their bioactive potential. Further studies on the selected endophytes may lead to the isolation of novel natural products for use in medicine, industry and agriculture.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 217 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 <1%
India 1 <1%
Italy 1 <1%
Germany 1 <1%
Unknown 213 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 54 25%
Student > Master 28 13%
Researcher 24 11%
Student > Bachelor 20 9%
Student > Postgraduate 19 9%
Other 49 23%
Unknown 23 11%
Readers by discipline Count As %
Agricultural and Biological Sciences 105 48%
Biochemistry, Genetics and Molecular Biology 24 11%
Chemistry 18 8%
Immunology and Microbiology 13 6%
Environmental Science 6 3%
Other 19 9%
Unknown 32 15%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 December 2016.
All research outputs
#6,757,931
of 22,693,205 outputs
Outputs from SpringerPlus
#419
of 1,852 outputs
Outputs of similar age
#74,433
of 282,285 outputs
Outputs of similar age from SpringerPlus
#8
of 73 outputs
Altmetric has tracked 22,693,205 research outputs across all sources so far. This one has received more attention than most of these and is in the 69th percentile.
So far Altmetric has tracked 1,852 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one has done well, scoring higher than 77% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 282,285 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.
We're also able to compare this research output to 73 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 89% of its contemporaries.