↓ Skip to main content

Mechanisms of action of naturally occurring antibodies against β-amyloid on microglia

Overview of attention for article published in Journal of Neuroinflammation, January 2013
Altmetric Badge

Citations

dimensions_citation
23 Dimensions

Readers on

mendeley
33 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Mechanisms of action of naturally occurring antibodies against β-amyloid on microglia
Published in
Journal of Neuroinflammation, January 2013
DOI 10.1186/1742-2094-10-5
Pubmed ID
Authors

Maike Gold, David Mengel, Stephan Röskam, Richard Dodel, Jan-Philipp Bach

Abstract

Naturally occurring autoantibodies against amyloid-β (nAbs-Aβ) have been shown to exert beneficial effects on transgenic Alzheimer's disease (AD) animals in vivo and on primary neurons in vitro. Not much is known about their effect on microglial cells. Our aim was to investigate the effect of nAbs-Aβ on amyloid-β (Aβ)-treated microglial cells in vitro with respect to cell viability, stress pathways, cytokine production and phagocytotic abilities and whether these effects can be conveyed to neurons.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 33 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 3%
Unknown 32 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 7 21%
Researcher 6 18%
Student > Bachelor 3 9%
Professor > Associate Professor 2 6%
Student > Master 2 6%
Other 4 12%
Unknown 9 27%
Readers by discipline Count As %
Agricultural and Biological Sciences 11 33%
Medicine and Dentistry 4 12%
Biochemistry, Genetics and Molecular Biology 2 6%
Neuroscience 2 6%
Chemistry 2 6%
Other 0 0%
Unknown 12 36%