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X Demographics
Mendeley readers
Attention Score in Context
| Title |
A near-infrared fluorophore for live-cell super-resolution microscopy of cellular proteins
|
|---|---|
| Published in |
Nature Chemistry, January 2013
|
| DOI | 10.1038/nchem.1546 |
| Pubmed ID | |
| Authors |
Gražvydas Lukinavičius, Keitaro Umezawa, Nicolas Olivier, Alf Honigmann, Guoying Yang, Tilman Plass, Veronika Mueller, Luc Reymond, Ivan R. Corrêa Jr, Zhen-Ge Luo, Carsten Schultz, Edward A. Lemke, Paul Heppenstall, Christian Eggeling, Suliana Manley, Kai Johnsson |
| Abstract |
The ideal fluorescent probe for bioimaging is bright, absorbs at long wavelengths and can be implemented flexibly in living cells and in vivo. However, the design of synthetic fluorophores that combine all of these properties has proved to be extremely difficult. Here, we introduce a biocompatible near-infrared silicon-rhodamine probe that can be coupled specifically to proteins using different labelling techniques. Importantly, its high permeability and fluorogenic character permit the imaging of proteins in living cells and tissues, and its brightness and photostability make it ideally suited for live-cell super-resolution microscopy. The excellent spectroscopic properties of the probe combined with its ease of use in live-cell applications make it a powerful new tool for bioimaging. |
X Demographics
The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Switzerland | 1 | 20% |
| Denmark | 1 | 20% |
| United Kingdom | 1 | 20% |
| China | 1 | 20% |
| Japan | 1 | 20% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 80% |
| Scientists | 1 | 20% |
Mendeley readers
The data shown below were compiled from readership statistics for 952 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 10 | 1% |
| United Kingdom | 8 | <1% |
| United States | 8 | <1% |
| France | 6 | <1% |
| Netherlands | 3 | <1% |
| Portugal | 2 | <1% |
| Switzerland | 2 | <1% |
| Mexico | 2 | <1% |
| Australia | 1 | <1% |
| Other | 8 | <1% |
| Unknown | 902 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 260 | 27% |
| Researcher | 190 | 20% |
| Student > Master | 109 | 11% |
| Student > Bachelor | 94 | 10% |
| Student > Doctoral Student | 40 | 4% |
| Other | 118 | 12% |
| Unknown | 141 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Chemistry | 274 | 29% |
| Agricultural and Biological Sciences | 185 | 19% |
| Biochemistry, Genetics and Molecular Biology | 146 | 15% |
| Physics and Astronomy | 74 | 8% |
| Engineering | 43 | 5% |
| Other | 75 | 8% |
| Unknown | 155 | 16% |
Attention Score in Context
This research output has an Altmetric Attention Score of 39. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 February 2024.
All research outputs
#1,056,071
of 25,457,858 outputs
Outputs from Nature Chemistry
#860
of 3,351 outputs
Outputs of similar age
#8,511
of 289,268 outputs
Outputs of similar age from Nature Chemistry
#7
of 54 outputs
Altmetric has tracked 25,457,858 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,351 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 36.0. This one has gotten more attention than average, scoring higher than 74% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 289,268 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 54 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 88% of its contemporaries.