Title |
MotifLab: a tools and data integration workbench for motif discovery and regulatory sequence analysis
|
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Published in |
BMC Bioinformatics, January 2013
|
DOI | 10.1186/1471-2105-14-9 |
Pubmed ID | |
Authors |
Kjetil Klepper, Finn Drabløs |
Abstract |
Traditional methods for computational motif discovery often suffer from poor performance. In particular, methods that search for sequence matches to known binding motifs tend to predict many non-functional binding sites because they fail to take into consideration the biological state of the cell. In recent years, genome-wide studies have generated a lot of data that has the potential to improve our ability to identify functional motifs and binding sites, such as information about chromatin accessibility and epigenetic states in different cell types. However, it is not always trivial to make use of this data in combination with existing motif discovery tools, especially for researchers who are not skilled in bioinformatics programming. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 2 | 50% |
United States | 1 | 25% |
Norway | 1 | 25% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Scientists | 3 | 75% |
Members of the public | 1 | 25% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 5 | 4% |
Germany | 4 | 3% |
Australia | 2 | 2% |
United Kingdom | 1 | <1% |
Finland | 1 | <1% |
Spain | 1 | <1% |
Mexico | 1 | <1% |
Unknown | 100 | 87% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 37 | 32% |
Student > Ph. D. Student | 24 | 21% |
Student > Master | 16 | 14% |
Professor > Associate Professor | 8 | 7% |
Student > Bachelor | 7 | 6% |
Other | 13 | 11% |
Unknown | 10 | 9% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 50 | 43% |
Biochemistry, Genetics and Molecular Biology | 25 | 22% |
Computer Science | 16 | 14% |
Medicine and Dentistry | 4 | 3% |
Engineering | 2 | 2% |
Other | 5 | 4% |
Unknown | 13 | 11% |