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Understanding the Role of Keratins 8 and 18 in Neoplastic Potential of Breast Cancer Derived Cell Lines

Overview of attention for article published in PLOS ONE, January 2013
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Title
Understanding the Role of Keratins 8 and 18 in Neoplastic Potential of Breast Cancer Derived Cell Lines
Published in
PLOS ONE, January 2013
DOI 10.1371/journal.pone.0053532
Pubmed ID
Authors

Sapna V. Iyer, Prerana P. Dange, Hunain Alam, Sharada S. Sawant, Arvind D. Ingle, Anita M. Borges, Neelam V. Shirsat, Sorab N. Dalal, Milind M. Vaidya

Abstract

Breast cancer is a complex disease which cannot be defined merely by clinical parameters like lymph node involvement and histological grade, or by routinely used biomarkers like estrogen receptor (ER), progesterone receptor (PGR) and epidermal growth factor receptor 2 (HER2) in diagnosis and prognosis. Breast cancer originates from the epithelial cells. Keratins (K) are cytoplasmic intermediate filament proteins of epithelial cells and changes in the expression pattern of keratins have been seen during malignant transformation in the breast. Expression of the K8/18 pair is seen in the luminal cells of the breast epithelium, and its role in prognostication of breast cancer is not well understood.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 88 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Finland 1 1%
Malaysia 1 1%
India 1 1%
Unknown 85 97%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 19 22%
Student > Ph. D. Student 16 18%
Student > Master 10 11%
Researcher 6 7%
Professor 5 6%
Other 17 19%
Unknown 15 17%
Readers by discipline Count As %
Agricultural and Biological Sciences 24 27%
Biochemistry, Genetics and Molecular Biology 21 24%
Medicine and Dentistry 10 11%
Unspecified 2 2%
Physics and Astronomy 2 2%
Other 12 14%
Unknown 17 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 January 2013.
All research outputs
#20,178,948
of 22,693,205 outputs
Outputs from PLOS ONE
#172,882
of 193,724 outputs
Outputs of similar age
#271,328
of 306,291 outputs
Outputs of similar age from PLOS ONE
#3,980
of 4,841 outputs
Altmetric has tracked 22,693,205 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 193,724 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.0. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 306,291 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 4,841 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.