Why is there variability in reactivation of the #FXN gene with #HDACinhibitors across a cohort of samples? Research from @LayneRodden, et al correlates #methylation and #reactivation. This research was funded in part by the #FARAGrantProgram. #CureFA https
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Epigenetic Heterogeneity in Friedreich Ataxia Underlies Variable FXN Reactivation https://t.co/FTd4faGPhY https://t.co/VOL4MdSqvU
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New Research: Epigenetic Heterogeneity in Friedreich Ataxia Underlies Variable FXN Reactivation: Friedreich ataxia (FRDA) is typically caused by homozygosity for an expanded GAA triplet-repeat in intron 1 of the FXN gene. The expanded… https://t.co/E8Iq4pq