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XACT, a long noncoding transcript coating the active X chromosome in human pluripotent cells

Overview of attention for article published in Nature Genetics, January 2013
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (92nd percentile)
  • Above-average Attention Score compared to outputs of the same age and source (58th percentile)

Mentioned by

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21 X users
facebook
1 Facebook page
wikipedia
1 Wikipedia page
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1 research highlight platform

Citations

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124 Dimensions

Readers on

mendeley
275 Mendeley
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2 CiteULike
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Title
XACT, a long noncoding transcript coating the active X chromosome in human pluripotent cells
Published in
Nature Genetics, January 2013
DOI 10.1038/ng.2530
Pubmed ID
Authors

Céline Vallot, Christophe Huret, Yann Lesecque, Alissa Resch, Noufissa Oudrhiri, Annelise Bennaceur-Griscelli, Laurent Duret, Claire Rougeulle

Abstract

X-chromosome inactivation (XCI) in mammals relies on XIST, a long noncoding transcript that coats and silences the X chromosome in cis. Here we report the discovery of a long noncoding RNA, XACT, that is expressed from and coats the active X chromosome specifically in human pluripotent cells. In the absence of XIST, XACT is expressed from both X chromosomes in humans but not in mice, suggesting a unique role for XACT in the control of human XCI initiation.

X Demographics

X Demographics

The data shown below were collected from the profiles of 21 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 275 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 4 1%
United States 3 1%
Germany 1 <1%
Finland 1 <1%
France 1 <1%
Portugal 1 <1%
Singapore 1 <1%
Canada 1 <1%
Japan 1 <1%
Other 1 <1%
Unknown 260 95%

Demographic breakdown

Readers by professional status Count As %
Researcher 67 24%
Student > Ph. D. Student 61 22%
Student > Master 33 12%
Student > Bachelor 28 10%
Professor > Associate Professor 18 7%
Other 37 13%
Unknown 31 11%
Readers by discipline Count As %
Agricultural and Biological Sciences 133 48%
Biochemistry, Genetics and Molecular Biology 77 28%
Medicine and Dentistry 18 7%
Neuroscience 5 2%
Immunology and Microbiology 3 1%
Other 8 3%
Unknown 31 11%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 16. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 November 2019.
All research outputs
#2,295,861
of 25,301,208 outputs
Outputs from Nature Genetics
#2,862
of 7,554 outputs
Outputs of similar age
#22,663
of 298,458 outputs
Outputs of similar age from Nature Genetics
#34
of 79 outputs
Altmetric has tracked 25,301,208 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 7,554 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 43.0. This one has gotten more attention than average, scoring higher than 62% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 298,458 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 79 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 58% of its contemporaries.