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Post-mortem assessment in vascular dementia: advances and aspirations

Overview of attention for article published in BMC Medicine, August 2016
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (85th percentile)
  • Average Attention Score compared to outputs of the same age and source

Mentioned by

news
1 news outlet
twitter
4 tweeters
facebook
1 Facebook page
reddit
1 Redditor

Citations

dimensions_citation
39 Dimensions

Readers on

mendeley
81 Mendeley
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Title
Post-mortem assessment in vascular dementia: advances and aspirations
Published in
BMC Medicine, August 2016
DOI 10.1186/s12916-016-0676-5
Pubmed ID
Authors

Kirsty E. McAleese, Irina Alafuzoff, Andreas Charidimou, Jacques De Reuck, Lea T. Grinberg, Atticus H. Hainsworth, Tibor Hortobagyi, Paul Ince, Kurt Jellinger, Jing Gao, Raj N. Kalaria, Gabor G. Kovacs, Enikö Kövari, Seth Love, Mara Popovic, Olivia Skrobot, Ricardo Taipa, Dietmar R. Thal, David Werring, Stephen B. Wharton, Johannes Attems

Abstract

Cerebrovascular lesions are a frequent finding in the elderly population. However, the impact of these lesions on cognitive performance, the prevalence of vascular dementia, and the pathophysiology behind characteristic in vivo imaging findings are subject to controversy. Moreover, there are no standardised criteria for the neuropathological assessment of cerebrovascular disease or its related lesions in human post-mortem brains, and conventional histological techniques may indeed be insufficient to fully reflect the consequences of cerebrovascular disease. Here, we review and discuss both the neuropathological and in vivo imaging characteristics of cerebrovascular disease, prevalence rates of vascular dementia, and clinico-pathological correlations. We also discuss the frequent comorbidity of cerebrovascular pathology and Alzheimer's disease pathology, as well as the difficult and controversial issue of clinically differentiating between Alzheimer's disease, vascular dementia and mixed Alzheimer's disease/vascular dementia. Finally, we consider additional novel approaches to complement and enhance current post-mortem assessment of cerebral human tissue. Elucidation of the pathophysiology of cerebrovascular disease, clarification of characteristic findings of in vivo imaging and knowledge about the impact of combined pathologies are needed to improve the diagnostic accuracy of clinical diagnoses.

Twitter Demographics

The data shown below were collected from the profiles of 4 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 81 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 1 1%
Unknown 80 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 16 20%
Student > Bachelor 14 17%
Researcher 12 15%
Student > Master 9 11%
Unspecified 7 9%
Other 23 28%
Readers by discipline Count As %
Medicine and Dentistry 22 27%
Neuroscience 15 19%
Unspecified 12 15%
Psychology 7 9%
Nursing and Health Professions 5 6%
Other 20 25%

Attention Score in Context

This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 November 2017.
All research outputs
#1,122,702
of 12,167,359 outputs
Outputs from BMC Medicine
#928
of 1,944 outputs
Outputs of similar age
#37,311
of 260,320 outputs
Outputs of similar age from BMC Medicine
#26
of 49 outputs
Altmetric has tracked 12,167,359 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,944 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 33.6. This one has gotten more attention than average, scoring higher than 52% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 260,320 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 85% of its contemporaries.
We're also able to compare this research output to 49 others from the same source and published within six weeks on either side of this one. This one is in the 46th percentile – i.e., 46% of its contemporaries scored the same or lower than it.