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Pathogenic potential of Blastocystis hominis in laboratory mice

Overview of attention for article published in Parasitology Research, May 2010
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (70th percentile)
  • Good Attention Score compared to outputs of the same age and source (77th percentile)

Mentioned by

blogs
1 blog

Readers on

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64 Mendeley
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Title
Pathogenic potential of Blastocystis hominis in laboratory mice
Published in
Parasitology Research, May 2010
DOI 10.1007/s00436-010-1922-y
Pubmed ID
Authors

Hala S. Elwakil, Iman H. Hewedi

Abstract

Blastocystis hominis is a ubiquitous enteric protozoan whose pathogenic potential is still controversial. This study was carried out to clarify the pathogenecity of B. hominis infection and to study the proper number of parasites for mice infection. A total of 15 albino mice were orally inoculated with B. hominis and divided according to the inoculums, 10(2), 10(5), and 4 x 10(7) B. hominis forms/100 microl saline, into three groups consisting of five mice each, GI, GII GIII, respectively. In addition with group IV (uninfected control) consisting of five mice. All mice were sacrificed 2 weeks post-infection. The results revealed that all mice of GIII and two mice of GII got the infection while all mice of GI showed a completely negative result. Histopathological examination of large intestine on highly infected group (GIII) showed that B. hominis infiltrated the lamina propria, the submucosa, and the muscle layers in the form of collection of vacuolar forms. This was accompanied by active colitis with infiltration of mixed inflammatory cells. In conclusion, this study revealed that large number of B. hominis is essential for oral infection of mice and that vacuolar forms of B. hominis can invade the lamina propria, the submucosa, and even the muscle layers.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 64 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
France 1 2%
Unknown 63 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 11 17%
Student > Bachelor 9 14%
Researcher 8 13%
Student > Master 6 9%
Student > Doctoral Student 5 8%
Other 9 14%
Unknown 16 25%
Readers by discipline Count As %
Medicine and Dentistry 12 19%
Agricultural and Biological Sciences 11 17%
Biochemistry, Genetics and Molecular Biology 8 13%
Immunology and Microbiology 5 8%
Veterinary Science and Veterinary Medicine 3 5%
Other 7 11%
Unknown 18 28%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 June 2012.
All research outputs
#5,846,938
of 22,694,633 outputs
Outputs from Parasitology Research
#398
of 3,773 outputs
Outputs of similar age
#27,891
of 95,797 outputs
Outputs of similar age from Parasitology Research
#4
of 18 outputs
Altmetric has tracked 22,694,633 research outputs across all sources so far. This one has received more attention than most of these and is in the 74th percentile.
So far Altmetric has tracked 3,773 research outputs from this source. They receive a mean Attention Score of 2.7. This one has done well, scoring higher than 89% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 95,797 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.
We're also able to compare this research output to 18 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 77% of its contemporaries.