Title |
All Our Babies Cohort Study: recruitment of a cohort to predict women at risk of preterm birth through the examination of gene expression profiles and the environment
|
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Published in |
BMC Pregnancy and Childbirth, December 2010
|
DOI | 10.1186/1471-2393-10-87 |
Pubmed ID | |
Authors |
Sara K Gracie, Andrew W Lyon, Heather L Kehler, Craig E Pennell, Siobhan M Dolan, Deborah A McNeil, Jodi E Siever, Sheila W McDonald, Alan D Bocking, Stephen J Lye, Kathy M Hegadoren, David M Olson, Suzanne C Tough |
Abstract |
Preterm birth is the leading cause of perinatal morbidity and mortality. Risk factors for preterm birth include a personal or familial history of preterm delivery, ethnicity and low socioeconomic status yet the ability to predict preterm delivery before the onset of preterm labour evades clinical practice. Evidence suggests that genetics may play a role in the multi-factorial pathophysiology of preterm birth. The All Our Babies Study is an on-going community based longitudinal cohort study that was designed to establish a cohort of women to investigate how a women's genetics and environment contribute to the pathophysiology of preterm birth. Specifically this study will examine the predictive potential of maternal leukocytes for predicting preterm birth in non-labouring women through the examination of gene expression profiles and gene-environment interactions. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Canada | 2 | 1% |
Brazil | 1 | <1% |
Uruguay | 1 | <1% |
United Kingdom | 1 | <1% |
United States | 1 | <1% |
Unknown | 141 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 21 | 14% |
Researcher | 18 | 12% |
Student > Bachelor | 15 | 10% |
Student > Ph. D. Student | 13 | 9% |
Student > Doctoral Student | 8 | 5% |
Other | 27 | 18% |
Unknown | 45 | 31% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 37 | 25% |
Nursing and Health Professions | 13 | 9% |
Agricultural and Biological Sciences | 10 | 7% |
Biochemistry, Genetics and Molecular Biology | 6 | 4% |
Social Sciences | 6 | 4% |
Other | 26 | 18% |
Unknown | 49 | 33% |