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Integrating Phylodynamics and Epidemiology to Estimate Transmission Diversity in Viral Epidemics

Overview of attention for article published in PLoS Computational Biology, January 2013
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (93rd percentile)
  • High Attention Score compared to outputs of the same age and source (84th percentile)

Mentioned by

news
1 news outlet
twitter
10 X users
facebook
2 Facebook pages

Citations

dimensions_citation
54 Dimensions

Readers on

mendeley
171 Mendeley
citeulike
1 CiteULike
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Title
Integrating Phylodynamics and Epidemiology to Estimate Transmission Diversity in Viral Epidemics
Published in
PLoS Computational Biology, January 2013
DOI 10.1371/journal.pcbi.1002876
Pubmed ID
Authors

Gkikas Magiorkinis, Vana Sypsa, Emmanouil Magiorkinis, Dimitrios Paraskevis, Antigoni Katsoulidou, Robert Belshaw, Christophe Fraser, Oliver George Pybus, Angelos Hatzakis

Abstract

The epidemiology of chronic viral infections, such as those caused by Hepatitis C Virus (HCV) and Human Immunodeficiency Virus (HIV), is affected by the risk group structure of the infected population. Risk groups are defined by each of their members having acquired infection through a specific behavior. However, risk group definitions say little about the transmission potential of each infected individual. Variation in the number of secondary infections is extremely difficult to estimate for HCV and HIV but crucial in the design of efficient control interventions. Here we describe a novel method that combines epidemiological and population genetic approaches to estimate the variation in transmissibility of rapidly-evolving viral epidemics. We evaluate this method using a nationwide HCV epidemic and for the first time co-estimate viral generation times and superspreading events from a combination of molecular and epidemiological data. We anticipate that this integrated approach will form the basis of powerful tools for describing the transmission dynamics of chronic viral diseases, and for evaluating control strategies directed against them.

X Demographics

X Demographics

The data shown below were collected from the profiles of 10 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 171 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 7 4%
United Kingdom 5 3%
Brazil 2 1%
Kenya 1 <1%
Uruguay 1 <1%
Portugal 1 <1%
Belgium 1 <1%
Netherlands 1 <1%
Venezuela, Bolivarian Republic of 1 <1%
Other 1 <1%
Unknown 150 88%

Demographic breakdown

Readers by professional status Count As %
Researcher 48 28%
Student > Ph. D. Student 40 23%
Student > Master 17 10%
Student > Bachelor 15 9%
Professor 9 5%
Other 26 15%
Unknown 16 9%
Readers by discipline Count As %
Agricultural and Biological Sciences 61 36%
Medicine and Dentistry 36 21%
Biochemistry, Genetics and Molecular Biology 11 6%
Mathematics 9 5%
Immunology and Microbiology 7 4%
Other 17 10%
Unknown 30 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 18. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 November 2014.
All research outputs
#2,068,245
of 25,901,238 outputs
Outputs from PLoS Computational Biology
#1,801
of 9,068 outputs
Outputs of similar age
#19,421
of 293,151 outputs
Outputs of similar age from PLoS Computational Biology
#23
of 150 outputs
Altmetric has tracked 25,901,238 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 9,068 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 20.3. This one has done well, scoring higher than 80% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 293,151 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 93% of its contemporaries.
We're also able to compare this research output to 150 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 84% of its contemporaries.