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Production of LacZ Inducible T Cell Hybridoma Specific for Human and Mouse gp10025–33 Peptides

Overview of attention for article published in PLOS ONE, February 2013
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  • Good Attention Score compared to outputs of the same age (70th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (59th percentile)

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1 Facebook page

Citations

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52 Mendeley
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Title
Production of LacZ Inducible T Cell Hybridoma Specific for Human and Mouse gp10025–33 Peptides
Published in
PLOS ONE, February 2013
DOI 10.1371/journal.pone.0055583
Pubmed ID
Authors

Gal Cafri, Adi Sharbi-Yunger, Esther Tzehoval, Lea Eisenbach

Abstract

Identification and quantification of immunogenic peptides and tumor-derived epitopes presented on MHC-I molecules are essential for basic studies and vaccines generation. Although lymphocytes derived from transgenic mice can serve as sensitive detectors of processes of antigen presentation and recognition, they are not always available. The use of cell lines might be extremely useful. In this study, we generated a lacZ inducible CD8⁺ hybridoma (BUSA14) capable of recognizing both human and mouse gp100₂₅₋₃₃ melanoma antigens presented on dendritic and tumor cell lines. This hybridoma expresses a variety of membranal T cell markers and secretes IL-2 and TNFα. Thus, BUSA14 offers a quantifiable, cheap and straightforward tool for studying peptide presentation by MHC-I molecules on the cell surface.

X Demographics

X Demographics

The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 52 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 52 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 20 38%
Student > Bachelor 7 13%
Student > Master 6 12%
Other 4 8%
Researcher 2 4%
Other 4 8%
Unknown 9 17%
Readers by discipline Count As %
Agricultural and Biological Sciences 17 33%
Biochemistry, Genetics and Molecular Biology 9 17%
Immunology and Microbiology 9 17%
Chemistry 2 4%
Environmental Science 1 2%
Other 3 6%
Unknown 11 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 February 2013.
All research outputs
#7,179,818
of 22,694,633 outputs
Outputs from PLOS ONE
#84,928
of 193,729 outputs
Outputs of similar age
#81,358
of 282,530 outputs
Outputs of similar age from PLOS ONE
#1,894
of 5,001 outputs
Altmetric has tracked 22,694,633 research outputs across all sources so far. This one has received more attention than most of these and is in the 67th percentile.
So far Altmetric has tracked 193,729 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.0. This one has gotten more attention than average, scoring higher than 54% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 282,530 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.
We're also able to compare this research output to 5,001 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 59% of its contemporaries.