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Nicotinic Acid Receptor Abnormalities in Human Skin Cancer: Implications for a Role in Epidermal Differentiation

Overview of attention for article published in PLOS ONE, May 2011
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Title
Nicotinic Acid Receptor Abnormalities in Human Skin Cancer: Implications for a Role in Epidermal Differentiation
Published in
PLOS ONE, May 2011
DOI 10.1371/journal.pone.0020487
Pubmed ID
Authors

Yira Bermudez, Claudia A. Benavente, Ralph G. Meyer, W. Russell Coyle, Myron K. Jacobson, Elaine L. Jacobson

Abstract

Chronic UV skin exposure leads to epidermal differentiation defects in humans that can be largely restored by pharmacological doses of nicotinic acid. Nicotinic acid has been identified as a ligand for the human G-protein-coupled receptors GPR109A and GPR109B that signal through G(i)-mediated inhibition of adenylyl cyclase. We have examined the expression, cellular distribution, and functionality of GPR109A/B in human skin and skin derived epidermal cells.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 42 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 1 2%
Unknown 41 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 11 26%
Student > Ph. D. Student 8 19%
Student > Master 4 10%
Student > Bachelor 3 7%
Student > Doctoral Student 2 5%
Other 7 17%
Unknown 7 17%
Readers by discipline Count As %
Agricultural and Biological Sciences 12 29%
Biochemistry, Genetics and Molecular Biology 9 21%
Pharmacology, Toxicology and Pharmaceutical Science 3 7%
Medicine and Dentistry 3 7%
Computer Science 2 5%
Other 3 7%
Unknown 10 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 November 2023.
All research outputs
#20,377,121
of 25,914,360 outputs
Outputs from PLOS ONE
#178,831
of 226,134 outputs
Outputs of similar age
#104,768
of 124,051 outputs
Outputs of similar age from PLOS ONE
#1,434
of 1,746 outputs
Altmetric has tracked 25,914,360 research outputs across all sources so far. This one is in the 18th percentile – i.e., 18% of other outputs scored the same or lower than it.
So far Altmetric has tracked 226,134 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.9. This one is in the 17th percentile – i.e., 17% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 124,051 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 14th percentile – i.e., 14% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 1,746 others from the same source and published within six weeks on either side of this one. This one is in the 16th percentile – i.e., 16% of its contemporaries scored the same or lower than it.