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An S/T-Q cluster domain census unveils new putative targets under Tel1/Mec1 control

Overview of attention for article published in BMC Genomics, November 2012
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Title
An S/T-Q cluster domain census unveils new putative targets under Tel1/Mec1 control
Published in
BMC Genomics, November 2012
DOI 10.1186/1471-2164-13-664
Pubmed ID
Authors

Hannah C Cheung, F Anthony San Lucas, Stephanie Hicks, Kyle Chang, Alison A Bertuch, Albert Ribes-Zamora

Abstract

The cellular response to DNA damage is immediate and highly coordinated in order to maintain genome integrity and proper cell division. During the DNA damage response (DDR), the sensor kinases Tel1 and Mec1 in Saccharomyces cerevisiae and ATM and ATR in human, phosphorylate multiple mediators which activate effector proteins to initiate cell cycle checkpoints and DNA repair. A subset of kinase substrates are recognized by the S/T-Q cluster domain (SCD), which contains motifs of serine (S) or threonine (T) followed by a glutamine (Q). However, the full repertoire of proteins and pathways controlled by Tel1 and Mec1 is unknown.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 44 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 2 5%
United States 1 2%
Unknown 41 93%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 14 32%
Researcher 10 23%
Student > Master 7 16%
Student > Bachelor 5 11%
Professor > Associate Professor 4 9%
Other 4 9%
Readers by discipline Count As %
Agricultural and Biological Sciences 27 61%
Biochemistry, Genetics and Molecular Biology 15 34%
Mathematics 1 2%
Social Sciences 1 2%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 February 2013.
All research outputs
#18,327,422
of 22,694,633 outputs
Outputs from BMC Genomics
#8,146
of 10,616 outputs
Outputs of similar age
#214,526
of 276,439 outputs
Outputs of similar age from BMC Genomics
#295
of 379 outputs
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