Title |
Risks of Colorectal and Other Cancers After Endometrial Cancer for Women With Lynch Syndrome
|
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Published in |
JNCI: Journal of the National Cancer Institute, February 2013
|
DOI | 10.1093/jnci/djs525 |
Pubmed ID | |
Authors |
Aung Ko Win, Noralane M Lindor, Ingrid Winship, Katherine M Tucker, Daniel D Buchanan, Joanne P Young, Christophe Rosty, Barbara Leggett, Graham G Giles, Jack Goldblatt, Finlay A Macrae, Susan Parry, Matthew F Kalady, John A Baron, Dennis J Ahnen, Loic Le Marchand, Steven Gallinger, Robert W Haile, Polly A Newcomb, John L Hopper, Mark A Jenkins |
Abstract |
Lynch syndrome is an autosomal dominantly inherited disorder caused by germline mutations in DNA mismatch repair (MMR) genes. Previous studies have shown that MMR gene mutation carriers are at increased risk of colorectal, endometrial, and several other cancers following an initial diagnosis of colorectal cancer. We estimated cancer risks following an endometrial cancer diagnosis for women carrying MMR gene mutations. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 5 | 36% |
United Kingdom | 3 | 21% |
Canada | 1 | 7% |
Unknown | 5 | 36% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 9 | 64% |
Practitioners (doctors, other healthcare professionals) | 4 | 29% |
Scientists | 1 | 7% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Slovakia | 1 | 1% |
Brazil | 1 | 1% |
Unknown | 79 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 14 | 17% |
Student > Ph. D. Student | 13 | 16% |
Other | 9 | 11% |
Student > Master | 7 | 9% |
Student > Doctoral Student | 7 | 9% |
Other | 20 | 25% |
Unknown | 11 | 14% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 41 | 51% |
Agricultural and Biological Sciences | 10 | 12% |
Biochemistry, Genetics and Molecular Biology | 7 | 9% |
Social Sciences | 3 | 4% |
Business, Management and Accounting | 1 | 1% |
Other | 4 | 5% |
Unknown | 15 | 19% |