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Method for Quantitative Study of Airway Functional Microanatomy Using Micro-Optical Coherence Tomography

Overview of attention for article published in PLOS ONE, January 2013
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  • Good Attention Score compared to outputs of the same age (72nd percentile)
  • Above-average Attention Score compared to outputs of the same age and source (63rd percentile)

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1 X user
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2 patents
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1 Facebook page

Citations

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158 Dimensions

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119 Mendeley
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Title
Method for Quantitative Study of Airway Functional Microanatomy Using Micro-Optical Coherence Tomography
Published in
PLOS ONE, January 2013
DOI 10.1371/journal.pone.0054473
Pubmed ID
Authors

Linbo Liu, Kengyeh K. Chu, Grace H. Houser, Bradford J. Diephuis, Yao Li, Eric J. Wilsterman, Suresh Shastry, Gregory Dierksen, Susan E. Birket, Marina Mazur, Suzanne Byan-Parker, William E. Grizzle, Eric J. Sorscher, Steven M. Rowe, Guillermo J. Tearney

Abstract

We demonstrate the use of a high resolution form of optical coherence tomography, termed micro-OCT (μOCT), for investigating the functional microanatomy of airway epithelia. μOCT captures several key parameters governing the function of the airway surface (airway surface liquid depth, periciliary liquid depth, ciliary function including beat frequency, and mucociliary transport rate) from the same series of images and without exogenous particles or labels, enabling non-invasive study of dynamic phenomena. Additionally, the high resolution of μOCT reveals distinguishable phases of the ciliary stroke pattern and glandular extrusion. Images and functional measurements from primary human bronchial epithelial cell cultures and excised tissue are presented and compared with measurements using existing gold standard methods. Active secretion from mucus glands in tissue, a key parameter of epithelial function, was also observed and quantified.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 119 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 3 3%
Singapore 1 <1%
Unknown 115 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 39 33%
Researcher 24 20%
Student > Doctoral Student 9 8%
Professor > Associate Professor 9 8%
Student > Postgraduate 6 5%
Other 12 10%
Unknown 20 17%
Readers by discipline Count As %
Engineering 34 29%
Agricultural and Biological Sciences 18 15%
Medicine and Dentistry 17 14%
Physics and Astronomy 13 11%
Biochemistry, Genetics and Molecular Biology 4 3%
Other 10 8%
Unknown 23 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 February 2024.
All research outputs
#7,346,143
of 24,226,848 outputs
Outputs from PLOS ONE
#93,045
of 208,425 outputs
Outputs of similar age
#77,576
of 288,449 outputs
Outputs of similar age from PLOS ONE
#1,770
of 5,015 outputs
Altmetric has tracked 24,226,848 research outputs across all sources so far. This one has received more attention than most of these and is in the 69th percentile.
So far Altmetric has tracked 208,425 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.6. This one has gotten more attention than average, scoring higher than 54% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 288,449 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.
We're also able to compare this research output to 5,015 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 63% of its contemporaries.