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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Intervening with Urinary Tract Infections Using Anti-Adhesives Based on the Crystal Structure of the FimH–Oligomannose-3 Complex
|
|---|---|
| Published in |
PLOS ONE, April 2008
|
| DOI | 10.1371/journal.pone.0002040 |
| Pubmed ID | |
| Authors |
Adinda Wellens, Corinne Garofalo, Hien Nguyen, Nani Van Gerven, Rikard Slättegård, Jean-Pierre Hernalsteens, Lode Wyns, Stefan Oscarson, Henri De Greve, Scott Hultgren, Julie Bouckaert |
| Abstract |
Escherichia coli strains adhere to the normally sterile human uroepithelium using type 1 pili, that are long, hairy surface organelles exposing a mannose-binding FimH adhesin at the tip. A small percentage of adhered bacteria can successfully invade bladder cells, presumably via pathways mediated by the high-mannosylated uroplakin-Ia and alpha3beta1 integrins found throughout the uroepithelium. Invaded bacteria replicate and mature into dense, biofilm-like inclusions in preparation of fluxing and of infection of neighbouring cells, being the major cause of the troublesome recurrent urinary tract infections. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Netherlands | 1 | 33% |
| Unknown | 2 | 67% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 168 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 5 | 3% |
| United Kingdom | 1 | <1% |
| France | 1 | <1% |
| Nigeria | 1 | <1% |
| Denmark | 1 | <1% |
| Unknown | 159 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 37 | 22% |
| Researcher | 33 | 20% |
| Student > Bachelor | 14 | 8% |
| Student > Master | 11 | 7% |
| Professor | 10 | 6% |
| Other | 29 | 17% |
| Unknown | 34 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 45 | 27% |
| Chemistry | 18 | 11% |
| Medicine and Dentistry | 16 | 10% |
| Biochemistry, Genetics and Molecular Biology | 14 | 8% |
| Immunology and Microbiology | 13 | 8% |
| Other | 19 | 11% |
| Unknown | 43 | 26% |
Attention Score in Context
This research output has an Altmetric Attention Score of 22. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 July 2023.
All research outputs
#1,777,902
of 25,997,855 outputs
Outputs from PLOS ONE
#21,592
of 226,985 outputs
Outputs of similar age
#4,111
of 90,740 outputs
Outputs of similar age from PLOS ONE
#44
of 326 outputs
Altmetric has tracked 25,997,855 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 226,985 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.9. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 90,740 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 326 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 86% of its contemporaries.