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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Pentosan Polysulfate: A Novel Therapy for the Mucopolysaccharidoses
|
|---|---|
| Published in |
PLOS ONE, January 2013
|
| DOI | 10.1371/journal.pone.0054459 |
| Pubmed ID | |
| Authors |
Edward H. Schuchman, Yi Ge, Alon Lai, Yury Borisov, Meghan Faillace, Efrat Eliyahu, Xingxuan He, James Iatridis, Helen Vlassara, Gary Striker, Calogera M. Simonaro |
| Abstract |
Pentosan polysulfate (PPS) is an FDA-approved, oral medication with anti-inflammatory and pro-chondrogenic properties. We have previously shown that animal models of the mucopolysaccharidoses (MPS) exhibit significant inflammatory disease, contributing to cartilage degeneration. Enzyme replacement therapy (ERT) only partly reduced inflammation, and anti-TNF-alpha antibody therapy significantly enhanced clinical and pathological outcomes. Here we describe the use of PPS for the treatment of MPS type VI rats. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Australia | 1 | 50% |
| Spain | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Practitioners (doctors, other healthcare professionals) | 1 | 50% |
| Members of the public | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 80 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 3% |
| Netherlands | 1 | 1% |
| Brazil | 1 | 1% |
| Unknown | 76 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 10 | 13% |
| Researcher | 10 | 13% |
| Student > Master | 10 | 13% |
| Student > Bachelor | 8 | 10% |
| Other | 6 | 8% |
| Other | 14 | 18% |
| Unknown | 22 | 28% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 24 | 30% |
| Agricultural and Biological Sciences | 11 | 14% |
| Biochemistry, Genetics and Molecular Biology | 8 | 10% |
| Nursing and Health Professions | 4 | 5% |
| Chemistry | 3 | 4% |
| Other | 8 | 10% |
| Unknown | 22 | 28% |
Attention Score in Context
This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 July 2019.
All research outputs
#3,918,803
of 22,696,971 outputs
Outputs from PLOS ONE
#56,089
of 193,735 outputs
Outputs of similar age
#42,673
of 280,574 outputs
Outputs of similar age from PLOS ONE
#1,072
of 5,005 outputs
Altmetric has tracked 22,696,971 research outputs across all sources so far. Compared to these this one has done well and is in the 82nd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 193,735 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.0. This one has gotten more attention than average, scoring higher than 70% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 280,574 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 84% of its contemporaries.
We're also able to compare this research output to 5,005 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 78% of its contemporaries.