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Optimization of Class I Histone Deacetylase PROTACs Reveals that HDAC1/2 Degradation is Critical to Induce Apoptosis and Cell Arrest in Cancer Cells

Overview of attention for article published in Journal of Medicinal Chemistry, March 2022
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#23 of 22,333)
  • High Attention Score compared to outputs of the same age (98th percentile)
  • High Attention Score compared to outputs of the same age and source (98th percentile)

Mentioned by

news
17 news outlets
twitter
22 X users

Citations

dimensions_citation
34 Dimensions

Readers on

mendeley
49 Mendeley
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Title
Optimization of Class I Histone Deacetylase PROTACs Reveals that HDAC1/2 Degradation is Critical to Induce Apoptosis and Cell Arrest in Cancer Cells
Published in
Journal of Medicinal Chemistry, March 2022
DOI 10.1021/acs.jmedchem.1c02179
Pubmed ID
Authors

Joshua P. Smalley, India M. Baker, Wiktoria A. Pytel, Li-Ying Lin, Karen J. Bowman, John W. R. Schwabe, Shaun M. Cowley, James T. Hodgkinson

X Demographics

X Demographics

The data shown below were collected from the profiles of 22 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 49 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 49 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 8 16%
Researcher 5 10%
Student > Master 5 10%
Student > Doctoral Student 2 4%
Lecturer 1 2%
Other 4 8%
Unknown 24 49%
Readers by discipline Count As %
Chemistry 10 20%
Pharmacology, Toxicology and Pharmaceutical Science 6 12%
Biochemistry, Genetics and Molecular Biology 5 10%
Unspecified 1 2%
Agricultural and Biological Sciences 1 2%
Other 1 2%
Unknown 25 51%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 141. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 April 2022.
All research outputs
#257,523
of 23,479,361 outputs
Outputs from Journal of Medicinal Chemistry
#23
of 22,333 outputs
Outputs of similar age
#7,774
of 444,262 outputs
Outputs of similar age from Journal of Medicinal Chemistry
#3
of 168 outputs
Altmetric has tracked 23,479,361 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 22,333 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.7. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 444,262 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 168 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 98% of its contemporaries.