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Brain natriuretic peptide for prevention of contrast-inducednephropathy: a meta-analysis of randomized controlled trials

Overview of attention for article published in European Journal of Clinical Pharmacology, October 2016
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Title
Brain natriuretic peptide for prevention of contrast-inducednephropathy: a meta-analysis of randomized controlled trials
Published in
European Journal of Clinical Pharmacology, October 2016
DOI 10.1007/s00228-016-2135-9
Pubmed ID
Authors

Xue-biao Wei, Lei Jiang, Xin-rong Liu, Dan-qing Yu, Ning Tan, Ji-yan Chen, Ying-ling Zhou, Peng-cheng He, Yuan-hui Liu

Abstract

Contrast-induced nephropathy (CIN) is a serious complication and associated with poor clinical outcomes. The protective value of brain natriuretic peptide (BNP) administration on CIN is still controversial in patients undergoing percutaneous coronary intervention (PCI) or coronary angiography (CAG). We performed a meta-analysis of randomized controlled trials (RCTs) for BNP in preventing CIN. We systematically searched PubMed, Web of Science, Cochrane Library, and ClinicalTrials.gov for RCTs comparing administration of BNP versus non-BNP for preventing CIN. Publication bias was assessed by funnel plots. Relative risk (RR) was calculated for incidence of CIN and major adverse cardiovascular events (MACEs) using the random or fixed effect model according to heterogeneity analysis. There were five RCTs with 1441 patients in this analysis. BNP treatment was associated with lower incidence of CIN (RR = 0.38, 95 % CI 0.27-0.54, p < 0.001) and MACEs (RR = 0.47, 95 % CI 0.24-0.95, p = 0.034) with no significant heterogeneity (I (2) = 0 %, p = 0.701; I (2) = 60 %, p = 0.113, respectively). Similar results were seen in subgroup analysis. Prophylactic BNP significantly decreased the incidence of CIN after cardiac catheterization in the studies of regarding sodium chloride as placebo (I (2) = 0 %, RR = 0.39, 95 % CI 0.27-0.56, p < 0.001) or JADAD score > 3 (I (2) = 0 %, RR = 0.38, 95 % CI 0.21-0.68, p = 0.001). Preprocedural BNP treatment significantly decreased the incidence of CIN and short-term MACEs in patients undergoing PCI or CAG.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 25 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Kazakhstan 1 4%
Unknown 24 96%

Demographic breakdown

Readers by professional status Count As %
Other 7 28%
Student > Doctoral Student 3 12%
Student > Master 3 12%
Professor > Associate Professor 2 8%
Lecturer > Senior Lecturer 1 4%
Other 4 16%
Unknown 5 20%
Readers by discipline Count As %
Medicine and Dentistry 19 76%
Psychology 2 8%
Unknown 4 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 October 2016.
All research outputs
#14,273,624
of 22,890,496 outputs
Outputs from European Journal of Clinical Pharmacology
#1,949
of 2,564 outputs
Outputs of similar age
#185,567
of 324,317 outputs
Outputs of similar age from European Journal of Clinical Pharmacology
#10
of 15 outputs
Altmetric has tracked 22,890,496 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,564 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.0. This one is in the 22nd percentile – i.e., 22% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 324,317 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 15 others from the same source and published within six weeks on either side of this one. This one is in the 33rd percentile – i.e., 33% of its contemporaries scored the same or lower than it.