Complement Factor H-Related Proteins FHR1 and FHR5 Interact With Extracellular Matrix Ligands, Reduce Factor H Regulatory Activity and Enhance Complement Activation

Overview of attention for article published in Frontiers in immunology, March 2022

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RT @EccoComplement: PAPER OF THE WEEK Papp et al. showed that FHR-1 & FHR-5 bound to extracellular matrix (ECM) components. Interestingly,…

17 Apr 2022

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RT @EccoComplement: PAPER OF THE WEEK Papp et al. showed that FHR-1 & FHR-5 bound to extracellular matrix (ECM) components. Interestingly,…

14 Apr 2022

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RT @EccoComplement: PAPER OF THE WEEK Papp et al. showed that FHR-1 & FHR-5 bound to extracellular matrix (ECM) components. Interestingly,…

14 Apr 2022

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PAPER OF THE WEEK Papp et al. showed that FHR-1 & FHR-5 bound to extracellular matrix (ECM) components. Interestingly, FHR1 & FHR5 inhibited the binding of Factor H to the ECM proteins, resulting in ⬇️ Factor H cofactor activity. Read the full pa

14 Apr 2022

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