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Biological and therapeutic effects of ortho-silicic acid and some ortho-silicic acid-releasing compounds: New perspectives for therapy

Overview of attention for article published in Nutrition & Metabolism, January 2013
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (97th percentile)
  • High Attention Score compared to outputs of the same age and source (94th percentile)

Mentioned by

news
2 news outlets
blogs
1 blog
twitter
24 X users
patent
5 patents
facebook
6 Facebook pages
wikipedia
3 Wikipedia pages
googleplus
1 Google+ user
video
2 YouTube creators

Readers on

mendeley
266 Mendeley
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Title
Biological and therapeutic effects of ortho-silicic acid and some ortho-silicic acid-releasing compounds: New perspectives for therapy
Published in
Nutrition & Metabolism, January 2013
DOI 10.1186/1743-7075-10-2
Pubmed ID
Authors

Lela Munjas Jurkić, Ivica Cepanec, Sandra Kraljević Pavelić, Krešimir Pavelić

Abstract

Silicon (Si) is the most abundant element present in the Earth's crust besides oxygen. However, the exact biological roles of silicon remain unknown. Moreover, the ortho-silicic acid (H4SiO4), as a major form of bioavailable silicon for both humans and animals, has not been given adequate attention so far. Silicon has already been associated with bone mineralization, collagen synthesis, skin, hair and nails health atherosclerosis, Alzheimer disease, immune system enhancement, and with some other disorders or pharmacological effects. Beside the ortho-silicic acid and its stabilized formulations such as choline chloride-stabilized ortho-silicic acid and sodium or potassium silicates (e.g. M2SiO3; M= Na,K), the most important sources that release ortho-silicic acid as a bioavailable form of silicon are: colloidal silicic acid (hydrated silica gel), silica gel (amorphous silicon dioxide), and zeolites. Although all these compounds are characterized by substantial water insolubility, they release small, but significant, equilibrium concentration of ortho-silicic acid (H4SiO4) in contact with water and physiological fluids. Even though certain pharmacological effects of these compounds might be attributed to specific structural characteristics that result in profound adsorption and absorption properties, they all exhibit similar pharmacological profiles readily comparable to ortho-silicic acid effects. The most unusual ortho-silicic acid-releasing agents are certain types of zeolites, a class of aluminosilicates with well described ion(cation)-exchange properties. Numerous biological activities of some types of zeolites documented so far might probably be attributable to the ortho-silicic acid-releasing property. In this review, we therefore discuss biological and potential therapeutic effects of ortho-silicic acid and ortho-silicic acid -releasing silicon compounds as its major natural sources.

X Demographics

X Demographics

The data shown below were collected from the profiles of 24 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 266 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 <1%
Italy 1 <1%
Unknown 263 99%

Demographic breakdown

Readers by professional status Count As %
Researcher 52 20%
Student > Ph. D. Student 33 12%
Student > Master 33 12%
Other 21 8%
Student > Bachelor 21 8%
Other 49 18%
Unknown 57 21%
Readers by discipline Count As %
Agricultural and Biological Sciences 48 18%
Chemistry 23 9%
Biochemistry, Genetics and Molecular Biology 22 8%
Medicine and Dentistry 17 6%
Pharmacology, Toxicology and Pharmaceutical Science 16 6%
Other 63 24%
Unknown 77 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 53. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 October 2023.
All research outputs
#817,392
of 26,017,215 outputs
Outputs from Nutrition & Metabolism
#135
of 1,030 outputs
Outputs of similar age
#6,180
of 296,540 outputs
Outputs of similar age from Nutrition & Metabolism
#1
of 17 outputs
Altmetric has tracked 26,017,215 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,030 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 28.7. This one has done well, scoring higher than 86% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 296,540 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 17 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 94% of its contemporaries.