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Transcranial Electrical Currents to Probe EEG Brain Rhythms and Memory Consolidation during Sleep in Humans

Overview of attention for article published in PLOS ONE, February 2011
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Title
Transcranial Electrical Currents to Probe EEG Brain Rhythms and Memory Consolidation during Sleep in Humans
Published in
PLOS ONE, February 2011
DOI 10.1371/journal.pone.0016905
Pubmed ID
Authors

Lisa Marshall, Roumen Kirov, Julian Brade, Matthias Mölle, Jan Born

Abstract

Previously the application of a weak electric anodal current oscillating with a frequency of the sleep slow oscillation (∼0.75 Hz) during non-rapid eye movement sleep (NonREM) sleep boosted endogenous slow oscillation activity and enhanced sleep-associated memory consolidation. The slow oscillations occurring during NonREM sleep and theta oscillations present during REM sleep have been considered of critical relevance for memory formation. Here transcranial direct current stimulation (tDCS) oscillating at 5 Hz, i.e., within the theta frequency range (theta-tDCS) is applied during NonREM and REM sleep. Theta-tDCS during NonREM sleep produced a global decrease in slow oscillatory activity conjoint with a local reduction of frontal slow EEG spindle power (8-12 Hz) and a decrement in consolidation of declarative memory, underlining the relevance of these cortical oscillations for sleep-dependent memory consolidation. In contrast, during REM sleep theta-tDCS appears to increase global gamma (25-45 Hz) activity, indicating a clear brain state-dependency of theta-tDCS. More generally, results demonstrate the suitability of oscillating-tDCS as a tool to analyze functions of endogenous EEG rhythms and underlying endogenous electric fields as well as the interactions between EEG rhythms of different frequencies.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 408 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 5 1%
Switzerland 3 <1%
France 3 <1%
United States 3 <1%
Netherlands 2 <1%
Italy 2 <1%
United Kingdom 2 <1%
Japan 2 <1%
Lithuania 1 <1%
Other 5 1%
Unknown 380 93%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 90 22%
Researcher 76 19%
Student > Master 65 16%
Student > Bachelor 32 8%
Other 19 5%
Other 66 16%
Unknown 60 15%
Readers by discipline Count As %
Psychology 107 26%
Neuroscience 77 19%
Agricultural and Biological Sciences 55 13%
Medicine and Dentistry 48 12%
Engineering 14 3%
Other 22 5%
Unknown 85 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 February 2013.
All research outputs
#17,681,263
of 22,699,621 outputs
Outputs from PLOS ONE
#146,474
of 193,796 outputs
Outputs of similar age
#162,583
of 185,283 outputs
Outputs of similar age from PLOS ONE
#1,104
of 1,304 outputs
Altmetric has tracked 22,699,621 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 193,796 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.0. This one is in the 20th percentile – i.e., 20% of its peers scored the same or lower than it.
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We're also able to compare this research output to 1,304 others from the same source and published within six weeks on either side of this one. This one is in the 14th percentile – i.e., 14% of its contemporaries scored the same or lower than it.