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Influence of the Presence of Tissue Expanders on Energy Deposition for Post-Mastectomy Radiotherapy

Overview of attention for article published in PLOS ONE, February 2013
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Title
Influence of the Presence of Tissue Expanders on Energy Deposition for Post-Mastectomy Radiotherapy
Published in
PLOS ONE, February 2013
DOI 10.1371/journal.pone.0055430
Pubmed ID
Authors

Débora M. Trombetta, Simone C. Cardoso, Alessandro Facure, Ademir X. da Silva, Luiz Antonio R. da Rosa

Abstract

An increasing number of studies have shown that post-mastectomy radiotherapy presents benefits associated with the patients survival and a significant fraction of the treated patients makes use of tissue expanders for breast reconstruction. Some models of tissue expanders have a magnetic disk on their surface that constitutes heterogeneity in the radiation field, which can affect the dose distribution during the radiotherapy treatment. In this study, the influence of a metallic heterogeneity positioned in a breast tissue expander was evaluated by means of Monte Carlo simulations using the MCNPX code and using Eclipse treatment planning system. Deposited energy values were calculated in structures which have clinical importance for the treatment. Additionally, the effect in the absorbed energy due to backscattering and attenuation of the incident beam caused by the heterogeneity, as well as due to the expansion of the prosthesis, was evaluated in target structures for a 6 MV photon beam by simulations. The dose distributions for a breast treatment were calculated using a convolution/superposition algorithm from the Eclipse treatment planning system. When compared with the smallest breast expander volume, underdosage of 7% was found for the largest volume of breast implant, in the case of frontal irradiation of the chest wall, by Monte Carlo simulations. No significant changes were found in dose distributions for the presence of the heterogeneity during the treatment planning of irradiation with an opposed pair of beams. Even considering the limitation of the treatment planning system, the results obtained with its use confirm those ones found by Monte Carlo simulations for a tangent beam irradiation. The presence of a heterogeneity didn't alters the dose distributions on treatment structures. The underdosage of 7% observed with Monte Carlo simulations were found for irradiation at 0°, not used frequently in a clinical routine.

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Mendeley readers

The data shown below were compiled from readership statistics for 41 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 1 2%
Spain 1 2%
Unknown 39 95%

Demographic breakdown

Readers by professional status Count As %
Researcher 6 15%
Student > Postgraduate 5 12%
Student > Master 5 12%
Student > Bachelor 4 10%
Other 3 7%
Other 10 24%
Unknown 8 20%
Readers by discipline Count As %
Medicine and Dentistry 20 49%
Physics and Astronomy 7 17%
Psychology 2 5%
Business, Management and Accounting 1 2%
Agricultural and Biological Sciences 1 2%
Other 1 2%
Unknown 9 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 February 2013.
All research outputs
#15,265,264
of 22,699,621 outputs
Outputs from PLOS ONE
#130,070
of 193,796 outputs
Outputs of similar age
#182,447
of 282,968 outputs
Outputs of similar age from PLOS ONE
#3,180
of 5,040 outputs
Altmetric has tracked 22,699,621 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 193,796 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.0. This one is in the 24th percentile – i.e., 24% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 282,968 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 25th percentile – i.e., 25% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 5,040 others from the same source and published within six weeks on either side of this one. This one is in the 30th percentile – i.e., 30% of its contemporaries scored the same or lower than it.