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Quantifying the contribution of chromatin dynamics to stochastic gene expression reveals long, locus-dependent periods between transcriptional bursts

Overview of attention for article published in BMC Biology, February 2013
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Title
Quantifying the contribution of chromatin dynamics to stochastic gene expression reveals long, locus-dependent periods between transcriptional bursts
Published in
BMC Biology, February 2013
DOI 10.1186/1741-7007-11-15
Pubmed ID
Authors

José Viñuelas, Gaël Kaneko, Antoine Coulon, Elodie Vallin, Valérie Morin, Camila Mejia-Pous, Jean-Jacques Kupiec, Guillaume Beslon, Olivier Gandrillon

Abstract

A number of studies have established that stochasticity in gene expression may play an important role in many biological phenomena. This therefore calls for further investigations to identify the molecular mechanisms at stake, in order to understand and manipulate cell-to-cell variability. In this work, we explored the role played by chromatin dynamics in the regulation of stochastic gene expression in higher eukaryotic cells.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 103 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Portugal 2 2%
Chile 2 2%
United States 2 2%
France 2 2%
Netherlands 1 <1%
Germany 1 <1%
Unknown 93 90%

Demographic breakdown

Readers by professional status Count As %
Researcher 29 28%
Student > Ph. D. Student 25 24%
Student > Master 13 13%
Professor > Associate Professor 6 6%
Student > Bachelor 5 5%
Other 14 14%
Unknown 11 11%
Readers by discipline Count As %
Agricultural and Biological Sciences 52 50%
Biochemistry, Genetics and Molecular Biology 21 20%
Physics and Astronomy 8 8%
Engineering 3 3%
Computer Science 2 2%
Other 3 3%
Unknown 14 14%