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Exposures to Synthetic Estrogens at Different Times During the Life, and Their Effect on Breast Cancer Risk

Overview of attention for article published in Journal of Mammary Gland Biology and Neoplasia, February 2013
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • One of the highest-scoring outputs from this source (#9 of 384)
  • High Attention Score compared to outputs of the same age (94th percentile)

Mentioned by

news
2 news outlets
twitter
6 X users
facebook
2 Facebook pages
wikipedia
1 Wikipedia page

Readers on

mendeley
166 Mendeley
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Title
Exposures to Synthetic Estrogens at Different Times During the Life, and Their Effect on Breast Cancer Risk
Published in
Journal of Mammary Gland Biology and Neoplasia, February 2013
DOI 10.1007/s10911-013-9274-8
Pubmed ID
Authors

Leena Hilakivi-Clarke, Sonia de Assis, Anni Warri

Abstract

Women are using estrogens for many purposes, such as to prevent pregnancy or miscarriage, or to treat menopausal symptoms. Estrogens also have been used to treat breast cancer which seems puzzling, since there is convincing evidence to support a link between high lifetime estrogen exposure and increased breast cancer risk. In this review, we discuss the findings that maternal exposure to the synthetic estrogen diethylstilbestrol during pregnancy increases breast cancer risk in both exposed mothers and their daughters. In addition, we review data regarding the use of estrogens in oral contraceptives and as postmenopausal hormone therapy and discuss the opposing effects on breast cancer risk based upon timing of exposure. We place particular emphasis on studies investigating how maternal estrogenic exposures during pregnancy increase breast cancer risk among daughters. New data suggest that these exposures induce epigenetic modifications in the mammary gland and germ cells, thereby causing an inheritable increase in breast cancer risk for multiple generations.

X Demographics

X Demographics

The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 166 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Chile 1 <1%
Unknown 165 99%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 28 17%
Student > Master 27 16%
Student > Ph. D. Student 20 12%
Researcher 10 6%
Student > Doctoral Student 10 6%
Other 21 13%
Unknown 50 30%
Readers by discipline Count As %
Medicine and Dentistry 34 20%
Agricultural and Biological Sciences 27 16%
Biochemistry, Genetics and Molecular Biology 24 14%
Pharmacology, Toxicology and Pharmaceutical Science 6 4%
Nursing and Health Professions 5 3%
Other 18 11%
Unknown 52 31%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 22. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 April 2023.
All research outputs
#1,687,333
of 25,270,999 outputs
Outputs from Journal of Mammary Gland Biology and Neoplasia
#9
of 384 outputs
Outputs of similar age
#15,995
of 296,710 outputs
Outputs of similar age from Journal of Mammary Gland Biology and Neoplasia
#2
of 4 outputs
Altmetric has tracked 25,270,999 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 384 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.2. This one has done particularly well, scoring higher than 97% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 296,710 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 94% of its contemporaries.
We're also able to compare this research output to 4 others from the same source and published within six weeks on either side of this one. This one has scored higher than 2 of them.