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H-RN, a peptide derived from hepatocyte growth factor, inhibits corneal neovascularization by inducing endothelial apoptosis and arresting the cell cycle

Overview of attention for article published in BMC Cell Biology, January 2013
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About this Attention Score

  • Among the highest-scoring outputs from this source (#40 of 249)
  • Good Attention Score compared to outputs of the same age (73rd percentile)
  • High Attention Score compared to outputs of the same age and source (83rd percentile)

Mentioned by

twitter
1 tweeter
patent
1 patent

Citations

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12 Dimensions

Readers on

mendeley
9 Mendeley
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Title
H-RN, a peptide derived from hepatocyte growth factor, inhibits corneal neovascularization by inducing endothelial apoptosis and arresting the cell cycle
Published in
BMC Cell Biology, January 2013
DOI 10.1186/1471-2121-14-8
Pubmed ID
Authors

Ye Sun, Li Su, Zhongxiao Wang, Yi Xu, Xun Xu

Abstract

The goal of this study was to investigate the anti-angiogenic activity of a novel peptide H-RN, derived from the hepatocyte growth factor kringle 1 domain (HGF K1), in a mouse model of corneal neovascularization. The anti-angiogenic effect of H-RN on vascular endothelial growth factor (VEGF)-stimulated cell proliferation, cell migration and endothelial cell tube formation was assessed in vitro using Human Umbilical Vein Endothelial Cells (HUVECs) and in vivo using a mouse cornea micropocket assay. Apoptosis and cell cycle arrest were assessed by flow cytometry. A scrambled peptide was used as a negative control.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 9 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 9 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 2 22%
Student > Ph. D. Student 2 22%
Researcher 2 22%
Student > Master 1 11%
Professor > Associate Professor 1 11%
Other 1 11%
Readers by discipline Count As %
Agricultural and Biological Sciences 4 44%
Medicine and Dentistry 3 33%
Pharmacology, Toxicology and Pharmaceutical Science 1 11%
Veterinary Science and Veterinary Medicine 1 11%

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 March 2017.
All research outputs
#2,441,352
of 9,522,333 outputs
Outputs from BMC Cell Biology
#40
of 249 outputs
Outputs of similar age
#31,973
of 122,363 outputs
Outputs of similar age from BMC Cell Biology
#1
of 6 outputs
Altmetric has tracked 9,522,333 research outputs across all sources so far. This one has received more attention than most of these and is in the 73rd percentile.
So far Altmetric has tracked 249 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.0. This one has done well, scoring higher than 82% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 122,363 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.
We're also able to compare this research output to 6 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them