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Effect of Zinc Supplementation on the Status of Thyroid Hormones and Na, K, and Ca Levels in Blood Following Ethanol Feeding

Overview of attention for article published in Biological Trace Element Research, April 2010
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Title
Effect of Zinc Supplementation on the Status of Thyroid Hormones and Na, K, and Ca Levels in Blood Following Ethanol Feeding
Published in
Biological Trace Element Research, April 2010
DOI 10.1007/s12011-010-8691-4
Pubmed ID
Authors

R. Pathak, D. Dhawan, A. Pathak

Abstract

The influence of zinc (Zn) on the serum levels of triiodothyronine (T(3)), thyroxine (T(4)), thyroid-stimulating hormone (TSH) and sodium (Na), potassium (K), and calcium (Ca) was evaluated following ethanol toxicity to the rats. To achieve this, male Wistar rats (150-195 g) were given 3 ml of 30% ethanol orally, and zinc was given in the form of zinc sulfate (227 mg/l) in their drinking water daily for 8 weeks. Ethanol feeding resulted in a slight decrease in T(3) and T(4) levels and a significant increase in thyroid-stimulating hormone concentration, which may be due to the direct stimulatory effect of ethanol on thyroid. Interestingly, when zinc was given to these rats, all the above levels were brought quite close to their normal levels, thus indicating the positive role of zinc in thyroid hormone metabolism. Serum Zn and Ca levels were found to be reduced, but Na levels were raised upon ethanol feeding. Restoration of normal levels of these metals upon zinc supplementation to ethanol fed rats confirms that zinc has potential in alleviating some of the altered thyroid functions following ethanol administration.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 13 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 13 100%

Demographic breakdown

Readers by professional status Count As %
Professor > Associate Professor 1 8%
Student > Bachelor 1 8%
Researcher 1 8%
Student > Doctoral Student 1 8%
Unknown 9 69%
Readers by discipline Count As %
Pharmacology, Toxicology and Pharmaceutical Science 2 15%
Medicine and Dentistry 2 15%
Nursing and Health Professions 1 8%
Unknown 8 62%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 December 2012.
All research outputs
#20,184,694
of 22,699,621 outputs
Outputs from Biological Trace Element Research
#1,565
of 2,013 outputs
Outputs of similar age
#90,498
of 94,986 outputs
Outputs of similar age from Biological Trace Element Research
#16
of 18 outputs
Altmetric has tracked 22,699,621 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,013 research outputs from this source. They receive a mean Attention Score of 4.7. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 94,986 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 18 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.