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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Enhanced Fluorescent Assignment of Protein Aggregates by an Oligothiophene–Porphyrin‐Based Amyloid Ligand
|
|---|---|
| Published in |
Macromolecular Rapid Communications, March 2013
|
| DOI | 10.1002/marc.201200817 |
| Pubmed ID | |
| Authors |
Katriann Arja, Daniel Sjölander, Alma Åslund, Stefan Prokop, Frank L. Heppner, Peter Konradsson, Mikael Lindgren, Per Hammarström, K. O. Andreas Åslund, K. Peter R. Nilsson |
| Abstract |
Fluorescent probes identifying protein aggregates are of great interest, as deposition of aggregated proteins is associated with many devastating diseases. Here, we report that a fluorescent amyloid ligand composed of two distinct molecular moieties, an amyloidophilic pentameric oligothiophene and a porphyrin, can be utilized for spectral and lifetime imaging assessment of recombinant Aβ 1-42 amyloid fibrils and Aβ deposits in brain tissue sections from a transgenic mouse model with Alzheimer's disease pathology. The enhanced spectral range and distinct lifetime diversity of this novel oligothiophene-porphyrin-based ligand allow a more precise assessment of heterogeneous amyloid morphology compared with the corresponding oligothiophene dye. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 36 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Sweden | 1 | 3% |
| Argentina | 1 | 3% |
| Unknown | 34 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 10 | 28% |
| Student > Ph. D. Student | 9 | 25% |
| Student > Master | 4 | 11% |
| Student > Bachelor | 4 | 11% |
| Professor > Associate Professor | 2 | 6% |
| Other | 2 | 6% |
| Unknown | 5 | 14% |
| Readers by discipline | Count | As % |
|---|---|---|
| Chemistry | 10 | 28% |
| Agricultural and Biological Sciences | 8 | 22% |
| Biochemistry, Genetics and Molecular Biology | 3 | 8% |
| Pharmacology, Toxicology and Pharmaceutical Science | 2 | 6% |
| Medicine and Dentistry | 2 | 6% |
| Other | 5 | 14% |
| Unknown | 6 | 17% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 March 2013.
All research outputs
#21,885,607
of 24,417,958 outputs
Outputs from Macromolecular Rapid Communications
#2,289
of 3,001 outputs
Outputs of similar age
#175,138
of 198,460 outputs
Outputs of similar age from Macromolecular Rapid Communications
#43
of 79 outputs
Altmetric has tracked 24,417,958 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,001 research outputs from this source. They receive a mean Attention Score of 3.3. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 198,460 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 79 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.