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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Integrated Analysis of COX-2 and iNOS Derived Inflammatory Mediators in LPS-Stimulated RAW Macrophages Pre-Exposed to Echium plantagineum L. Bee Pollen Extract
|
|---|---|
| Published in |
PLOS ONE, March 2013
|
| DOI | 10.1371/journal.pone.0059131 |
| Pubmed ID | |
| Authors |
Eduarda Moita, Angel Gil-Izquierdo, Carla Sousa, Federico Ferreres, Luís R. Silva, Patrícia Valentão, Raúl Domínguez-Perles, Nieves Baenas, Paula B. Andrade |
| Abstract |
Oxidative stress and inflammation play important roles in disease development. This study intended to evaluate the anti-inflammatory and antioxidant potential of Echium plantagineum L. bee pollen to support its claimed health beneficial effects. The hydromethanol extract efficiently scavenged nitric oxide ((•)NO) although against superoxide (O2(•-)) it behaved as antioxidant at lower concentrations and as pro-oxidant at higher concentrations. The anti-inflammatory potential was evaluated in LPS-stimulated macrophages. The levels of (•)NO and L-citrulline decreased for all extract concentrations tested, while the levels of prostaglandins, their metabolites and isoprostanes, evaluated by UPLC-MS, decreased with low extract concentrations. So, E. plantagineum bee pollen extract can exert anti-inflammatory activity by reducing (•)NO and prostaglandins. The extract is able to scavenge the reactive species (•)NO and O2(•-) and reduce markers of oxidative stress in cells at low concentrations. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 100 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Malaysia | 1 | 1% |
| United States | 1 | 1% |
| Sweden | 1 | 1% |
| Brazil | 1 | 1% |
| Unknown | 96 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 18 | 18% |
| Student > Ph. D. Student | 16 | 16% |
| Researcher | 15 | 15% |
| Student > Master | 15 | 15% |
| Student > Doctoral Student | 6 | 6% |
| Other | 7 | 7% |
| Unknown | 23 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 22 | 22% |
| Biochemistry, Genetics and Molecular Biology | 11 | 11% |
| Pharmacology, Toxicology and Pharmaceutical Science | 10 | 10% |
| Medicine and Dentistry | 8 | 8% |
| Chemistry | 6 | 6% |
| Other | 14 | 14% |
| Unknown | 29 | 29% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 October 2013.
All research outputs
#17,682,134
of 22,701,287 outputs
Outputs from PLOS ONE
#146,491
of 193,818 outputs
Outputs of similar age
#142,292
of 195,228 outputs
Outputs of similar age from PLOS ONE
#3,700
of 5,438 outputs
Altmetric has tracked 22,701,287 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 193,818 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.0. This one is in the 20th percentile – i.e., 20% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 195,228 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 23rd percentile – i.e., 23% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 5,438 others from the same source and published within six weeks on either side of this one. This one is in the 26th percentile – i.e., 26% of its contemporaries scored the same or lower than it.