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Targeting Ferroptosis Vulnerability in Synovial Sarcoma: Is It All About ME1?

Overview of attention for article published in Clinical Cancer Research, June 2022
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (91st percentile)
  • Good Attention Score compared to outputs of the same age and source (75th percentile)

Mentioned by

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44 X users

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mendeley
2 Mendeley
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Title
Targeting Ferroptosis Vulnerability in Synovial Sarcoma: Is It All About ME1?
Published in
Clinical Cancer Research, June 2022
DOI 10.1158/1078-0432.ccr-22-1257
Pubmed ID
Authors

Vivek Subbiah, Boyi Gan

Abstract

Understanding metabolic dependencies and their therapeutic vulnerabilities are key to precision oncology. Malic enzyme1 (ME1) is frequently overexpressed in cancers with pro-tumorigenic effects. In contrast, consistent loss of ME1 expression in synovial sarcoma compared with other sarcomas indicates a unique ferroptosis liability for precision therapy in this form of cancer.

X Demographics

X Demographics

The data shown below were collected from the profiles of 44 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 2 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 2 100%

Demographic breakdown

Readers by professional status Count As %
Student > Postgraduate 1 50%
Unknown 1 50%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 1 50%
Unknown 1 50%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 22. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 March 2023.
All research outputs
#1,747,454
of 25,756,911 outputs
Outputs from Clinical Cancer Research
#1,278
of 13,307 outputs
Outputs of similar age
#38,942
of 446,024 outputs
Outputs of similar age from Clinical Cancer Research
#34
of 138 outputs
Altmetric has tracked 25,756,911 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 13,307 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.8. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 446,024 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 91% of its contemporaries.
We're also able to compare this research output to 138 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 75% of its contemporaries.