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X Demographics
Mendeley readers
Attention Score in Context
| Title |
High-Throughput Massively Parallel Sequencing for Fetal Aneuploidy Detection from Maternal Plasma
|
|---|---|
| Published in |
PLOS ONE, March 2013
|
| DOI | 10.1371/journal.pone.0057381 |
| Pubmed ID | |
| Authors |
Taylor J. Jensen, Tricia Zwiefelhofer, Roger C. Tim, Željko Džakula, Sung K. Kim, Amin R. Mazloom, Zhanyang Zhu, John Tynan, Tim Lu, Graham McLennan, Glenn E. Palomaki, Jacob A. Canick, Paul Oeth, Cosmin Deciu, Dirk van den Boom, Mathias Ehrich |
| Abstract |
Circulating cell-free (ccf) fetal DNA comprises 3-20% of all the cell-free DNA present in maternal plasma. Numerous research and clinical studies have described the analysis of ccf DNA using next generation sequencing for the detection of fetal aneuploidies with high sensitivity and specificity. We sought to extend the utility of this approach by assessing semi-automated library preparation, higher sample multiplexing during sequencing, and improved bioinformatic tools to enable a higher throughput, more efficient assay while maintaining or improving clinical performance. |
X Demographics
The data shown below were collected from the profiles of 8 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 38% |
| France | 1 | 13% |
| United Kingdom | 1 | 13% |
| Canada | 1 | 13% |
| Unknown | 2 | 25% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 6 | 75% |
| Members of the public | 2 | 25% |
Mendeley readers
The data shown below were compiled from readership statistics for 114 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 4 | 4% |
| Korea, Republic of | 2 | 2% |
| Ireland | 1 | <1% |
| India | 1 | <1% |
| Sweden | 1 | <1% |
| Unknown | 105 | 92% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 33 | 29% |
| Student > Master | 19 | 17% |
| Student > Ph. D. Student | 14 | 12% |
| Student > Bachelor | 14 | 12% |
| Other | 13 | 11% |
| Other | 17 | 15% |
| Unknown | 4 | 4% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 52 | 46% |
| Biochemistry, Genetics and Molecular Biology | 27 | 24% |
| Medicine and Dentistry | 15 | 13% |
| Nursing and Health Professions | 3 | 3% |
| Computer Science | 3 | 3% |
| Other | 8 | 7% |
| Unknown | 6 | 5% |
Attention Score in Context
This research output has an Altmetric Attention Score of 17. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 March 2024.
All research outputs
#2,191,496
of 25,604,262 outputs
Outputs from PLOS ONE
#26,707
of 223,361 outputs
Outputs of similar age
#17,420
of 208,341 outputs
Outputs of similar age from PLOS ONE
#606
of 5,421 outputs
Altmetric has tracked 25,604,262 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 223,361 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.8. This one has done well, scoring higher than 88% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 208,341 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 91% of its contemporaries.
We're also able to compare this research output to 5,421 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 88% of its contemporaries.