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Monitoring cartilage loss in the hands and wrists in rheumatoid arthritis with magnetic resonance imaging in a multi-center clinical trial: IMPRESS (NCT00425932)

Overview of attention for article published in Arthritis Research & Therapy, March 2013
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Title
Monitoring cartilage loss in the hands and wrists in rheumatoid arthritis with magnetic resonance imaging in a multi-center clinical trial: IMPRESS (NCT00425932)
Published in
Arthritis Research & Therapy, March 2013
DOI 10.1186/ar4202
Pubmed ID
Authors

Charles G Peterfy, Ewa Olech, Julie C DiCarlo, Joan T Merrill, Peter J Countryman, Norman B Gaylis

Abstract

Magnetic resonance imaging (MRI) is increasingly being used in clinical trials of rheumatoid arthritis (RA) because of its superiority over x-ray radiography (XR) in detecting and monitoring change in bone erosion, osteitis and synovitis. However, in contrast to XR, the MRI scoring method that was used in most clinical trials did not include cartilage loss. This limitation has been an obstacle to accepting MRI as a potential alternative to XR in clinical trials. Cross-sectional studies have shown MRI to be sensitive for cartilage loss in the hands and wrist; although, longitudinal sensitivity to change has not yet been confirmed. In this study we examined the ability of MRI to monitor change in cartilage loss in patients with RA in a multi-site clinical trial setting.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 69 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 1%
Unknown 68 99%

Demographic breakdown

Readers by professional status Count As %
Student > Master 11 16%
Researcher 11 16%
Student > Bachelor 9 13%
Other 6 9%
Student > Doctoral Student 4 6%
Other 11 16%
Unknown 17 25%
Readers by discipline Count As %
Medicine and Dentistry 25 36%
Pharmacology, Toxicology and Pharmaceutical Science 5 7%
Biochemistry, Genetics and Molecular Biology 3 4%
Engineering 3 4%
Psychology 2 3%
Other 10 14%
Unknown 21 30%