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Diagnostic accuracy of early urinary index changes in differentiating transient frompersistent acute kidney injury in critically ill patients: multicenter cohortstudy

Overview of attention for article published in Critical Care, March 2013
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (83rd percentile)
  • Good Attention Score compared to outputs of the same age and source (77th percentile)

Mentioned by

blogs
1 blog
twitter
3 X users

Citations

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61 Dimensions

Readers on

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88 Mendeley
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1 CiteULike
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Title
Diagnostic accuracy of early urinary index changes in differentiating transient frompersistent acute kidney injury in critically ill patients: multicenter cohortstudy
Published in
Critical Care, March 2013
DOI 10.1186/cc12582
Pubmed ID
Authors

Bertrand Pons, Alexandre Lautrette, Johanna Oziel, Jean Dellamonica, Régine Vermesch, Eric Ezingeard, Christophe Mariat, Gilles Bernardin, Fabrice Zeni, Yves Cohen, Bernard Tardy, Bertrand Souweine, François Vincent, Michael Darmon

Abstract

INTRODUCTION: Urinary indices have limited effectiveness in separating transient acute kidney injury (AKI) from persistent AKI in ICU patients. Their time-course may vary with the mechanism of AKI. The primary objective of this study was to evaluate the diagnostic value of changes over time of the usual urinary indices in separating transient AKI from persistent AKI. METHODS: An observational prospective multicenter study was performed in six ICUs involving 244 consecutive patients, including 97 without AKI, 54 with transient AKI, and 93 with persistent AKI. Urinary sodium, urea and creatinine were measured at ICU admission (H0) and on 6-hour urine samples during the first 24 ICU hours (H6, H12, H18, and H24). Transient AKI was defined as AKI with a cause for renal hypoperfusion and reversal within 3 days. RESULTS: Significant increases from H0 to H24 were noted in fractional excretion of urea (median, 31% (22 to 41%) and 39% (29 to 48%) at H24, P < 0.0001), urinary urea/plasma urea ratio (15 (7 to 28) and 20 (9 to 40), P < 0.0001), and urinary creatinine/plasma creatinine ratio (50 (24 to 101) and 57 (29 to 104), P = 0.01). Fractional excretion of sodium did not change significantly during the first 24 hours in the ICU (P = 0.13). Neither urinary index values at ICU admission nor changes in urinary indices between H0 and H24 performed sufficiently well to recommend their use in clinical setting (area under the receiver-operating characteristic curve ≤0.65). CONCLUSION: Although urinary indices at H24 performed slightly better than those at H0 in differentiating transient AKI from persistent AKI, they remain insufficiently reliable to be clinically relevant.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 88 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 1 1%
Unknown 87 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 11 13%
Researcher 11 13%
Student > Postgraduate 9 10%
Other 8 9%
Professor 4 5%
Other 12 14%
Unknown 33 38%
Readers by discipline Count As %
Medicine and Dentistry 47 53%
Biochemistry, Genetics and Molecular Biology 2 2%
Agricultural and Biological Sciences 2 2%
Engineering 2 2%
Unknown 35 40%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 August 2017.
All research outputs
#4,168,063
of 25,373,627 outputs
Outputs from Critical Care
#2,981
of 6,554 outputs
Outputs of similar age
#33,704
of 210,387 outputs
Outputs of similar age from Critical Care
#38
of 167 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. Compared to these this one has done well and is in the 83rd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 6,554 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 20.8. This one has gotten more attention than average, scoring higher than 54% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 210,387 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 83% of its contemporaries.
We're also able to compare this research output to 167 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 77% of its contemporaries.