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Exciting Times beyond the Brain: Metabotropic Glutamate Receptors in Peripheral and Non-Neural Tissues

Overview of attention for article published in Pharmacological Reviews, January 2011
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (70th percentile)

Mentioned by

28 patents
2 Facebook pages


150 Dimensions

Readers on

201 Mendeley
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Exciting Times beyond the Brain: Metabotropic Glutamate Receptors in Peripheral and Non-Neural Tissues
Published in
Pharmacological Reviews, January 2011
DOI 10.1124/pr.110.004036
Pubmed ID

Marcela Julio-Pieper, Peter J. Flor, Timothy G. Dinan, John F. Cryan


Metabotropic glutamate (mGlu) receptors are G-protein-coupled receptors expressed primarily on neurons and glial cells, where they are located in the proximity of the synaptic cleft. In the central nervous system (CNS), mGlu receptors modulate the effects of l-glutamate neurotransmission in addition to that of a variety of other neurotransmitters. However, mGlu receptors also have a widespread distribution outside the CNS that has been somewhat neglected to date. Based on this expression, diverse roles of mGlu receptors have been suggested in a variety of processes in health and disease including controlling hormone production in the adrenal gland and pancreas, regulating mineralization in the developing cartilage, modulating lymphocyte cytokine production, directing the state of differentiation in embryonic stem cells, and modulating gastrointestinal secretory function. Understanding the role of mGlu receptors in the periphery will also provide a better insight into potential side effects of drugs currently being developed for neurological and psychiatric conditions. This review summarizes the new potential roles of mGlu receptors and raises the possibility of novel pharmacological targets for various disorders.

Mendeley readers

The data shown below were compiled from readership statistics for 201 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 4 2%
United Kingdom 3 1%
Ireland 1 <1%
Finland 1 <1%
Denmark 1 <1%
Canada 1 <1%
Unknown 190 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 44 22%
Researcher 36 18%
Student > Bachelor 24 12%
Student > Master 21 10%
Professor 11 5%
Other 27 13%
Unknown 38 19%
Readers by discipline Count As %
Agricultural and Biological Sciences 55 27%
Medicine and Dentistry 24 12%
Biochemistry, Genetics and Molecular Biology 17 8%
Neuroscience 17 8%
Pharmacology, Toxicology and Pharmaceutical Science 17 8%
Other 28 14%
Unknown 43 21%

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 June 2022.
All research outputs
of 22,757,090 outputs
Outputs from Pharmacological Reviews
of 652 outputs
Outputs of similar age
of 181,260 outputs
Outputs of similar age from Pharmacological Reviews
of 8 outputs
Altmetric has tracked 22,757,090 research outputs across all sources so far. This one has received more attention than most of these and is in the 68th percentile.
So far Altmetric has tracked 652 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.4. This one is in the 39th percentile – i.e., 39% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 181,260 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.
We're also able to compare this research output to 8 others from the same source and published within six weeks on either side of this one. This one has scored higher than 2 of them.