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The prevalence of drug resistance among treatment-naïve HIV-1-infected individuals in China during pre- and post- 2004

Overview of attention for article published in BMC Infectious Diseases, October 2016
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Title
The prevalence of drug resistance among treatment-naïve HIV-1-infected individuals in China during pre- and post- 2004
Published in
BMC Infectious Diseases, October 2016
DOI 10.1186/s12879-016-1928-x
Pubmed ID
Authors

Hanping Li, Shuai Chang, Yang Han, Daomin Zhuang, Lin Li, Yongjian Liu, Siyang Liu, Zuoyi Bao, Wenfu Zhang, Hongbin Song, Taisheng Li, Jingyun Li

Abstract

The widespread use of antiretroviral therapies has led to considerable concerns about the prevalence of drug-resistant, as transmission of drug-resistant (TDR) strains poses a challenge for the control of the HIV-1 epidemic. We conducted an epidemiological study enrolling treatment-naïve HIV-1-positive subjects at the Peking Union Medical College Hospital since 1991. Drug resistance was determined by submitting the sequences to the Stanford University Network HIV-1 database. Of 521 participants, 478 samples were amplified and sequenced successfully. HIV Transmitted drug resistance prevalence in China was determined to be 6.7 %. We did not find significant differences in the TDR rate by demographic characteristics. No significant time trend in the prevalence of overall TDR was observed (p > 0.05). We identified an intermediate prevalence of transmitted drug resistance (TDR), exhibiting a stable time trend. These findings enhance our understanding of HIV-1 drug resistance prevalence and time trend, and provide some guidelines for the comprehensive public health strategy of TDR prevention.

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The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 32 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 32 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 7 22%
Other 5 16%
Researcher 4 13%
Student > Ph. D. Student 2 6%
Student > Doctoral Student 1 3%
Other 3 9%
Unknown 10 31%
Readers by discipline Count As %
Medicine and Dentistry 7 22%
Biochemistry, Genetics and Molecular Biology 2 6%
Immunology and Microbiology 2 6%
Social Sciences 2 6%
Psychology 2 6%
Other 5 16%
Unknown 12 38%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 May 2017.
All research outputs
#14,869,124
of 22,899,952 outputs
Outputs from BMC Infectious Diseases
#4,097
of 7,691 outputs
Outputs of similar age
#187,935
of 314,048 outputs
Outputs of similar age from BMC Infectious Diseases
#113
of 224 outputs
Altmetric has tracked 22,899,952 research outputs across all sources so far. This one is in the 33rd percentile – i.e., 33% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,691 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.6. This one is in the 41st percentile – i.e., 41% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 314,048 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 37th percentile – i.e., 37% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 224 others from the same source and published within six weeks on either side of this one. This one is in the 46th percentile – i.e., 46% of its contemporaries scored the same or lower than it.