Title |
Dietary glycemic index and retinal microvasculature in adults: a cross-sectional study
|
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Published in |
Nutrition Journal, October 2016
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DOI | 10.1186/s12937-016-0209-2 |
Pubmed ID | |
Authors |
Natalia Sanchez-Aguadero, Rosario Alonso-Dominguez, Jose I. Recio-Rodriguez, Maria C. Patino-Alonso, Manuel A. Gomez-Marcos, Carlos Martin-Cantera, Yolanda Schmolling-Guinovart, Luis Garcia-Ortiz, the EVIDENT II Group |
Abstract |
To analyze the relationship between dietary glycemic index (GI) and retinal microvasculature in adults. This was a cross-sectional study of 300 subjects from the EVIDENT II study. Dietary GI was calculated using a validated, semi-quantitative food frequency questionnaire. Retinal photographs were digitized, temporal vessels were measured in an area 0.5-1 disc diameter from the optic disc and arteriolar-venular index (AVI) was estimated with semi-automated software. AVI showed a significant difference between the tertiles of GI, after adjusting for potential confounders. The lowest AVI values were observed among subjects in the highest tertile of GI, whereas the greatest were found among those in the lowest tertile (estimated marginal mean of 0.738 vs. 0.768, p = 0.014). In adults, high dietary GI implies lowering AVI values regardless of age, gender and other confounding variables. Clinical Trials.gov Identifier: NCT02016014 . Registered 9 December 2013. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 50% |
Canada | 1 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 29 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 5 | 17% |
Student > Doctoral Student | 4 | 14% |
Researcher | 3 | 10% |
Professor | 2 | 7% |
Professor > Associate Professor | 2 | 7% |
Other | 5 | 17% |
Unknown | 8 | 28% |
Readers by discipline | Count | As % |
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Nursing and Health Professions | 7 | 24% |
Medicine and Dentistry | 6 | 21% |
Economics, Econometrics and Finance | 2 | 7% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 3% |
Biochemistry, Genetics and Molecular Biology | 1 | 3% |
Other | 2 | 7% |
Unknown | 10 | 34% |