Title |
Selective targeting of melanoma by PEG-masked protein-based multifunctional nanoparticles
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Published in |
International Journal of Nanomedicine, March 2012
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DOI | 10.2147/ijn.s28242 |
Pubmed ID | |
Authors |
Luca Vannucci, Elisabetta Falvo, Manuela Fornara, Patrizio Di Micco, Oldrich Benada, Jiri Krizan, Jan Svoboda, Katarina Hulikova-Capkova, Veronica Morea, Alberto Boffi, Pierpaolo Ceci |
Abstract |
Nanoparticle-based systems are promising for the development of imaging and therapeutic agents. The main advantage of nanoparticles over traditional systems lies in the possibility of loading multiple functionalities onto a single molecule, which are useful for therapeutic and/or diagnostic purposes. These functionalities include targeting moieties which are able to recognize receptors overexpressed by specific cells and tissues. However, targeted delivery of nanoparticles requires an accurate system design. We present here a rationally designed, genetically engineered, and chemically modified protein-based nanoplatform for cell/tissue-specific targeting. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Switzerland | 1 | 1% |
Netherlands | 1 | 1% |
France | 1 | 1% |
United Kingdom | 1 | 1% |
Singapore | 1 | 1% |
United States | 1 | 1% |
Unknown | 71 | 92% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 21 | 27% |
Researcher | 12 | 16% |
Student > Master | 10 | 13% |
Student > Doctoral Student | 7 | 9% |
Student > Bachelor | 4 | 5% |
Other | 7 | 9% |
Unknown | 16 | 21% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 16 | 21% |
Chemistry | 13 | 17% |
Agricultural and Biological Sciences | 12 | 16% |
Medicine and Dentistry | 8 | 10% |
Materials Science | 3 | 4% |
Other | 7 | 9% |
Unknown | 18 | 23% |