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Elf5 - breast cancer's little helper

Overview of attention for article published in Breast Cancer Research, March 2013
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Title
Elf5 - breast cancer's little helper
Published in
Breast Cancer Research, March 2013
DOI 10.1186/bcr3397
Pubmed ID
Authors

Hayley T Frend, Christine J Watson

Abstract

A variety of transcription factors has been shown to regulate lineage commitment in the mammary gland and to be associated with different molecular subtypes of breast cancer. E74-like factor 5 (Elf5) has now been identified as a marker of oestrogen receptor status, and high expression correlates with more aggressive basal cancers and resistance to anti-oestrogens. Manipulation of Elf5 transcript levels perturbs the molecular profiles of luminal and basal subtypes, highlighting the possibility that targeting Elf5 could provide a new approach for the treatment of basal cancers.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 26 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 26 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 6 23%
Student > Master 4 15%
Student > Bachelor 3 12%
Researcher 3 12%
Professor 2 8%
Other 3 12%
Unknown 5 19%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 6 23%
Agricultural and Biological Sciences 6 23%
Medicine and Dentistry 5 19%
Nursing and Health Professions 1 4%
Psychology 1 4%
Other 1 4%
Unknown 6 23%