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Chondro-osseous respiratory epithelial adenomatoid hamartoma of the nasal cavity

Overview of attention for article published in International Archives of Otorhinolaryngology, January 2014
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Title
Chondro-osseous respiratory epithelial adenomatoid hamartoma of the nasal cavity
Published in
International Archives of Otorhinolaryngology, January 2014
DOI 10.7162/s1809-97772013000200017
Pubmed ID
Authors

Faysal Fedda, Fouad Boulos, Alain Sabri

Abstract

 Chondro-osseous respiratory epithelial adenomatoid hamartoma (COREAH) is a benign lesion of the nose and sinuses that is extremely rare, with only 2 cases reported in the literature to date.  We present herein the third reported case of COREAH, in a 38-year-old woman who presented with left nasal obstruction and a mass in her left nasal cavity. The mass was completely resected endoscopically. Microscopic examination showed hamartomatous proliferation of respiratory-type glands with mucinous metaplasia admixed with numerous spicules of mature bone, characteristic of COREAH.  COREAH is a benign hamartomatous proliferation of respiratory epithelium, submucosal glands, and chondro-osseous mesenchyme. The clinical differential diagnoses for such lesions include glandular hamartoma, inflammatory polyp, inverted papilloma, and low-grade sinonasal adenocarcinoma. Recognition of this lesion as benign despite its potentially worrisome radiographic appearance is important to avoid an unnecessarily radical surgical procedure.

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Mendeley readers

The data shown below were compiled from readership statistics for 8 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 8 100%

Demographic breakdown

Readers by professional status Count As %
Professor > Associate Professor 3 38%
Student > Bachelor 1 13%
Student > Doctoral Student 1 13%
Researcher 1 13%
Librarian 1 13%
Other 0 0%
Unknown 1 13%
Readers by discipline Count As %
Medicine and Dentistry 4 50%
Computer Science 1 13%
Pharmacology, Toxicology and Pharmaceutical Science 1 13%
Unknown 2 25%