Title |
The role of zebrafish (Danio rerio) in dissecting the genetics and neural circuits of executive function
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Published in |
Frontiers in Neural Circuits, January 2013
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DOI | 10.3389/fncir.2013.00063 |
Pubmed ID | |
Authors |
Matthew O. Parker, Alistair J. Brock, Robert T. Walton, Caroline H. Brennan |
Abstract |
Zebrafish have great potential to contribute to our understanding of behavioral genetics and thus to contribute to our understanding of the etiology of psychiatric disease. However, progress is dependent upon the rate at which behavioral assays addressing complex behavioral phenotypes are designed, reported and validated. Here we critically review existing behavioral assays with particular focus on the use of adult zebrafish to explore executive processes and phenotypes associated with human psychiatric disease. We outline the case for using zebrafish as models to study impulse control and attention, discussing the validity of applying extant rodent assays to zebrafish and evidence for the conservation of relevant neural circuits. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 33% |
Unknown | 2 | 67% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 3 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Portugal | 3 | 1% |
France | 3 | 1% |
United Kingdom | 3 | 1% |
United States | 3 | 1% |
Argentina | 1 | <1% |
Netherlands | 1 | <1% |
Spain | 1 | <1% |
China | 1 | <1% |
Unknown | 231 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 47 | 19% |
Student > Ph. D. Student | 43 | 17% |
Student > Master | 31 | 13% |
Student > Bachelor | 29 | 12% |
Student > Doctoral Student | 18 | 7% |
Other | 42 | 17% |
Unknown | 37 | 15% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 80 | 32% |
Neuroscience | 52 | 21% |
Biochemistry, Genetics and Molecular Biology | 19 | 8% |
Medicine and Dentistry | 12 | 5% |
Psychology | 12 | 5% |
Other | 20 | 8% |
Unknown | 52 | 21% |