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Clinical pancreatic islet transplantation

Overview of attention for article published in Nature Reviews Endocrinology, November 2016
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (94th percentile)
  • High Attention Score compared to outputs of the same age and source (84th percentile)

Mentioned by

news
1 news outlet
blogs
1 blog
twitter
30 X users
patent
3 patents
facebook
1 Facebook page
wikipedia
3 Wikipedia pages

Citations

dimensions_citation
557 Dimensions

Readers on

mendeley
547 Mendeley
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Title
Clinical pancreatic islet transplantation
Published in
Nature Reviews Endocrinology, November 2016
DOI 10.1038/nrendo.2016.178
Pubmed ID
Authors

A. M. James Shapiro, Marta Pokrywczynska, Camillo Ricordi

Abstract

Clinical pancreatic islet transplantation can be considered one of the safest and least invasive transplant procedures. Remarkable progress has occurred in both the technical aspects of islet cell processing and the outcomes of clinical islet transplantation. With >1,500 patients treated since 2000, this therapeutic strategy has moved from a curiosity to a realistic treatment option for selected patients with type 1 diabetes mellitus (that is, those with hypoglycaemia unawareness, severe hypoglycaemic episodes and glycaemic lability). This Review outlines the techniques required for human islet isolation, in vitro culture before the transplant and clinical islet transplantation, and discusses indications, optimization of recipient immunosuppression and management of adjunctive immunomodulatory and anti-inflammatory strategies. The potential risks, long-term outcomes and advances in treatment after the transplant are also discussed to further move this treatment towards becoming a more widely available option for patients with type 1 diabetes mellitus and eventually a potential cure.

X Demographics

X Demographics

The data shown below were collected from the profiles of 30 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 547 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 <1%
Unknown 546 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 98 18%
Student > Ph. D. Student 92 17%
Researcher 57 10%
Student > Master 55 10%
Student > Doctoral Student 30 5%
Other 67 12%
Unknown 148 27%
Readers by discipline Count As %
Medicine and Dentistry 105 19%
Biochemistry, Genetics and Molecular Biology 103 19%
Agricultural and Biological Sciences 45 8%
Engineering 44 8%
Immunology and Microbiology 11 2%
Other 63 12%
Unknown 176 32%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 39. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 January 2024.
All research outputs
#1,025,115
of 25,147,320 outputs
Outputs from Nature Reviews Endocrinology
#308
of 2,443 outputs
Outputs of similar age
#18,786
of 317,626 outputs
Outputs of similar age from Nature Reviews Endocrinology
#8
of 45 outputs
Altmetric has tracked 25,147,320 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,443 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 24.0. This one has done well, scoring higher than 87% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 317,626 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 94% of its contemporaries.
We're also able to compare this research output to 45 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 84% of its contemporaries.