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A nuclear localization for Avr2 from Fusarium oxysporum is required to activate the tomato resistance protein I-2

Overview of attention for article published in Frontiers in Plant Science, January 2013
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (60th percentile)

Mentioned by

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5 tweeters
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1 Facebook page

Citations

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23 Dimensions

Readers on

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74 Mendeley
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Title
A nuclear localization for Avr2 from Fusarium oxysporum is required to activate the tomato resistance protein I-2
Published in
Frontiers in Plant Science, January 2013
DOI 10.3389/fpls.2013.00094
Pubmed ID
Authors

Lisong Ma, Ben J. C. Cornelissen, Frank L. W. Takken, Ma, Lisong, Cornelissen, Ben J.C., Takken, Frank L.W.

Abstract

Plant pathogens secrete effector proteins to promote host colonization. During infection of tomato xylem vessels, Fusarium oxysporum f. sp. lycopersici (Fol) secretes the Avr2 effector protein. Besides being a virulence factor, Avr2 is recognized intracellularly by the tomato I-2 resistance protein, resulting in the induction of host defenses. Here, we show that AVR2 is highly expressed in root- and xylem-colonizing hyphae three days post inoculation of roots. Co-expression of I-2 with AVR2 deletion constructs using agroinfiltration in Nicotiana benthamiana leaves revealed that, except for the N-terminal 17 amino acids, the entire AVR2 protein is required to trigger I-2-mediated cell death. The truncated Avr2 variants are still able to form homo-dimers, showing that the central region of Avr2 is required for dimerization. Simultaneous production of I-2 and Avr2 chimeras carrying various subcellular localization signals in N. benthamiana leaves revealed that a nuclear localization of Avr2 is required to trigger I-2-dependent cell death. Nuclear exclusion of Avr2 prevented its activation of I-2, suggesting that Avr2 is recognized by I-2 in the nucleus.

Twitter Demographics

The data shown below were collected from the profiles of 5 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 74 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 3%
Australia 1 1%
Colombia 1 1%
Unknown 70 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 19 26%
Researcher 16 22%
Student > Master 14 19%
Student > Bachelor 7 9%
Student > Doctoral Student 4 5%
Other 14 19%
Readers by discipline Count As %
Agricultural and Biological Sciences 61 82%
Biochemistry, Genetics and Molecular Biology 6 8%
Unspecified 4 5%
Engineering 2 3%
Chemistry 1 1%
Other 0 0%

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 May 2013.
All research outputs
#5,892,176
of 11,410,087 outputs
Outputs from Frontiers in Plant Science
#1,761
of 7,468 outputs
Outputs of similar age
#50,839
of 130,671 outputs
Outputs of similar age from Frontiers in Plant Science
#1
of 4 outputs
Altmetric has tracked 11,410,087 research outputs across all sources so far. This one is in the 47th percentile – i.e., 47% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,468 research outputs from this source. They receive a mean Attention Score of 3.0. This one has gotten more attention than average, scoring higher than 74% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 130,671 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 60% of its contemporaries.
We're also able to compare this research output to 4 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them