Title |
Plasmatic higher levels of homocysteine in Non-alcoholic fatty liver disease (NAFLD)
|
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Published in |
Nutrition Journal, April 2013
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DOI | 10.1186/1475-2891-12-37 |
Pubmed ID | |
Authors |
Sylene Coutinho Rampche de Carvalho, Maria Tereza Cartaxo Muniz, Maria Deozete Vieira Siqueira, Erika Rabelo Forte Siqueira, Adriana Vieira Gomes, Karina Alves Silva, Laís Carvalho Luma Bezerra, Vânia D’Almeida, Claudia Pinto Marques Souza de Oliveira, Leila Maria M Beltrão Pereira |
Abstract |
Non-alcoholic fatty liver disease (NAFLD) is a chronic liver disease, which includes a spectrum of hepatic pathology such as simple steatosis, steatohepatitis, fibrosis and cirrhosis. The increased serum levels of homocysteine (Hcy) may be associated with hepatic fat accumulation. Genetic mutations in the folate route may only mildly impair Hcy metabolism. The aim of this study was to investigate the relation between liver steatosis with plasma homocysteine level and MTHFR C677T and A1298C polymorphisms in Brazilian patients with NAFLD. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United Kingdom | 2 | 50% |
United States | 1 | 25% |
Unknown | 1 | 25% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 3 | 75% |
Practitioners (doctors, other healthcare professionals) | 1 | 25% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Lebanon | 1 | 2% |
Belgium | 1 | 2% |
Australia | 1 | 2% |
Brazil | 1 | 2% |
Unknown | 54 | 93% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 11 | 19% |
Researcher | 8 | 14% |
Student > Ph. D. Student | 7 | 12% |
Student > Bachelor | 6 | 10% |
Student > Doctoral Student | 4 | 7% |
Other | 11 | 19% |
Unknown | 11 | 19% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 21 | 36% |
Agricultural and Biological Sciences | 7 | 12% |
Nursing and Health Professions | 4 | 7% |
Biochemistry, Genetics and Molecular Biology | 3 | 5% |
Computer Science | 2 | 3% |
Other | 6 | 10% |
Unknown | 15 | 26% |