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Solution structure of the Drosha double-stranded RNA-binding domain

Overview of attention for article published in Silence, January 2010
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (82nd percentile)

Mentioned by

blogs
1 blog

Citations

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24 Dimensions

Readers on

mendeley
61 Mendeley
citeulike
1 CiteULike
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Title
Solution structure of the Drosha double-stranded RNA-binding domain
Published in
Silence, January 2010
DOI 10.1186/1758-907x-1-2
Pubmed ID
Authors

Geoffrey A Mueller, Matthew T Miller, Eugene F DeRose, Mahua Ghosh, Robert E London, Traci M Tanaka Hall

Abstract

Drosha is a nuclear RNase III enzyme that initiates processing of regulatory microRNA. Together with partner protein DiGeorge syndrome critical region 8 (DGCR8), it forms the Microprocessor complex, which cleaves precursor transcripts called primary microRNA to produce hairpin precursor microRNA. In addition to two RNase III catalytic domains, Drosha contains a C-terminal double-stranded RNA-binding domain (dsRBD). To gain insight into the function of this domain, we determined the nuclear magnetic resonance (NMR) solution structure.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 61 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 1 2%
France 1 2%
Brazil 1 2%
South Africa 1 2%
United States 1 2%
Unknown 56 92%

Demographic breakdown

Readers by professional status Count As %
Researcher 16 26%
Student > Ph. D. Student 13 21%
Student > Doctoral Student 6 10%
Student > Master 6 10%
Professor > Associate Professor 5 8%
Other 10 16%
Unknown 5 8%
Readers by discipline Count As %
Agricultural and Biological Sciences 32 52%
Biochemistry, Genetics and Molecular Biology 11 18%
Chemistry 8 13%
Neuroscience 2 3%
Business, Management and Accounting 1 2%
Other 1 2%
Unknown 6 10%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 January 2010.
All research outputs
#5,423,170
of 25,374,917 outputs
Outputs from Silence
#11
of 28 outputs
Outputs of similar age
#29,531
of 173,741 outputs
Outputs of similar age from Silence
#2
of 3 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done well and is in the 78th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 28 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.8. This one scored the same or higher as 17 of them.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 173,741 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 82% of its contemporaries.
We're also able to compare this research output to 3 others from the same source and published within six weeks on either side of this one.