Title |
The genome of the crustacean Parhyale hawaiensis, a model for animal development, regeneration, immunity and lignocellulose digestion
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Published in |
eLife, November 2016
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DOI | 10.7554/elife.20062 |
Pubmed ID | |
Authors |
Damian Kao, Alvina G Lai, Evangelia Stamataki, Silvana Rosic, Nikolaos Konstantinides, Erin Jarvis, Alessia Di Donfrancesco, Natalia Pouchkina-Stancheva, Marie Semon, Marco Grillo, Heather Bruce, Suyash Kumar, Igor Siwanowicz, Andy Le, Andrew Lemire, Michael B Eisen, Cassandra Extavour, William E Browne, Carsten Wolff, Michalis Averof, Nipam H Patel, Peter Sarkies, Anastasios Pavlopoulos, Aziz Aboobaker |
Abstract |
The amphipod crustacean Parhyale hawaiensis is a blossoming model system for studies of developmental mechanisms and more recently regeneration. We have sequenced the genome allowing annotation of all key signaling pathways, transcription factors, and non-coding RNAs that will enhance ongoing functional studies. Parhyale is a member of the Malacostraca clade, which includes crustacean food crop species. We analysed the immunity related genes of Parhyale as an important comparative system for these species, where immunity related aquaculture problems have increased as farming has intensified. We also find that Parhyale and other species within Multicrustacea contain the enzyme sets necessary to perform lignocellulose digestion ('wood eating'), suggesting this ability may predate the diversification of this lineage. Our data provide an essential resource for further development of Parhyale as an experimental model. The first malacostracan genome will underpin ongoing comparative work in food crop species and research investigating lignocellulose as an energy source. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 10 | 15% |
United Kingdom | 8 | 12% |
Germany | 6 | 9% |
France | 4 | 6% |
India | 3 | 5% |
Japan | 2 | 3% |
Netherlands | 2 | 3% |
Spain | 2 | 3% |
Mexico | 1 | 2% |
Other | 6 | 9% |
Unknown | 21 | 32% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Scientists | 36 | 55% |
Members of the public | 28 | 43% |
Science communicators (journalists, bloggers, editors) | 1 | 2% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | <1% |
Unknown | 134 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 26 | 19% |
Researcher | 22 | 16% |
Student > Bachelor | 19 | 14% |
Student > Master | 10 | 7% |
Student > Doctoral Student | 9 | 7% |
Other | 18 | 13% |
Unknown | 31 | 23% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 40 | 30% |
Biochemistry, Genetics and Molecular Biology | 33 | 24% |
Environmental Science | 13 | 10% |
Computer Science | 3 | 2% |
Engineering | 2 | 1% |
Other | 8 | 6% |
Unknown | 36 | 27% |