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Mesenchymal Stem Cell-Mediated Functional Tooth Regeneration in Swine

Overview of attention for article published in PLOS ONE, December 2006
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (93rd percentile)
  • Good Attention Score compared to outputs of the same age and source (70th percentile)

Mentioned by

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2 X users
patent
2 patents
wikipedia
1 Wikipedia page

Citations

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1084 Dimensions

Readers on

mendeley
555 Mendeley
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1 CiteULike
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Title
Mesenchymal Stem Cell-Mediated Functional Tooth Regeneration in Swine
Published in
PLOS ONE, December 2006
DOI 10.1371/journal.pone.0000079
Pubmed ID
Authors

Wataru Sonoyama, Yi Liu, Dianji Fang, Takayoshi Yamaza, Byoung-Moo Seo, Chunmei Zhang, He Liu, Stan Gronthos, Cun-Yu Wang, Songtao Shi, Songlin Wang

Abstract

Mesenchymal stem cell-mediated tissue regeneration is a promising approach for regenerative medicine for a wide range of applications. Here we report a new population of stem cells isolated from the root apical papilla of human teeth (SCAP, stem cells from apical papilla). Using a minipig model, we transplanted both human SCAP and periodontal ligament stem cells (PDLSCs) to generate a root/periodontal complex capable of supporting a porcelain crown, resulting in normal tooth function. This work integrates a stem cell-mediated tissue regeneration strategy, engineered materials for structure, and current dental crown technologies. This hybridized tissue engineering approach led to recovery of tooth strength and appearance.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 555 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
France 3 <1%
Colombia 2 <1%
Brazil 2 <1%
United Kingdom 2 <1%
Iran, Islamic Republic of 2 <1%
Turkey 1 <1%
Germany 1 <1%
Korea, Republic of 1 <1%
Japan 1 <1%
Other 1 <1%
Unknown 539 97%

Demographic breakdown

Readers by professional status Count As %
Student > Master 94 17%
Student > Ph. D. Student 76 14%
Researcher 54 10%
Student > Bachelor 48 9%
Student > Postgraduate 39 7%
Other 100 18%
Unknown 144 26%
Readers by discipline Count As %
Medicine and Dentistry 228 41%
Agricultural and Biological Sciences 69 12%
Biochemistry, Genetics and Molecular Biology 35 6%
Engineering 17 3%
Materials Science 9 2%
Other 42 8%
Unknown 155 28%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 January 2020.
All research outputs
#2,688,929
of 22,707,247 outputs
Outputs from PLOS ONE
#34,344
of 193,889 outputs
Outputs of similar age
#10,234
of 156,137 outputs
Outputs of similar age from PLOS ONE
#38
of 127 outputs
Altmetric has tracked 22,707,247 research outputs across all sources so far. Compared to these this one has done well and is in the 87th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 193,889 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.0. This one has done well, scoring higher than 81% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 156,137 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 93% of its contemporaries.
We're also able to compare this research output to 127 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.