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Mendeley readers
Attention Score in Context
| Title |
Functional and comparative genomics analyses of pmp22 in medaka fish
|
|---|---|
| Published in |
BMC Neuroscience, June 2009
|
| DOI | 10.1186/1471-2202-10-60 |
| Pubmed ID | |
| Authors |
Junji Itou, Mikita Suyama, Yukio Imamura, Tomonori Deguchi, Kazuhiro Fujimori, Shunsuke Yuba, Yutaka Kawarabayasi, Takashi Kawasaki |
| Abstract |
Pmp22, a member of the junction protein family Claudin/EMP/PMP22, plays an important role in myelin formation. Increase of pmp22 transcription causes peripheral neuropathy, Charcot-Marie-Tooth disease type1A (CMT1A). The pathophysiological phenotype of CMT1A is aberrant axonal myelination which induces a reduction in nerve conduction velocity (NCV). Several CMT1A model rodents have been established by overexpressing pmp22. Thus, it is thought that pmp22 expression must be tightly regulated for correct myelin formation in mammals. Interestingly, the myelin sheath is also present in other jawed vertebrates. The purpose of this study is to analyze the evolutionary conservation of the association between pmp22 transcription level and vertebrate myelin formation, and to find the conserved non-coding sequences for pmp22 regulation by comparative genomics analyses between jawed fishes and mammals. |
Mendeley readers
The data shown below were compiled from readership statistics for 42 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 2% |
| Germany | 1 | 2% |
| Unknown | 40 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 7 | 17% |
| Researcher | 7 | 17% |
| Professor | 4 | 10% |
| Student > Bachelor | 4 | 10% |
| Lecturer | 2 | 5% |
| Other | 7 | 17% |
| Unknown | 11 | 26% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 11 | 26% |
| Biochemistry, Genetics and Molecular Biology | 5 | 12% |
| Medicine and Dentistry | 4 | 10% |
| Neuroscience | 3 | 7% |
| Nursing and Health Professions | 2 | 5% |
| Other | 5 | 12% |
| Unknown | 12 | 29% |
Attention Score in Context
This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 June 2009.
All research outputs
#5,477,369
of 22,707,247 outputs
Outputs from BMC Neuroscience
#241
of 1,240 outputs
Outputs of similar age
#29,472
of 110,545 outputs
Outputs of similar age from BMC Neuroscience
#6
of 20 outputs
Altmetric has tracked 22,707,247 research outputs across all sources so far. Compared to these this one has done well and is in the 75th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,240 research outputs from this source. They receive a mean Attention Score of 4.3. This one has done well, scoring higher than 80% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 110,545 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.
We're also able to compare this research output to 20 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.