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Expression of Regulatory Platelet MicroRNAs in Patients with Sickle Cell Disease

Overview of attention for article published in PLOS ONE, April 2013
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Title
Expression of Regulatory Platelet MicroRNAs in Patients with Sickle Cell Disease
Published in
PLOS ONE, April 2013
DOI 10.1371/journal.pone.0060932
Pubmed ID
Authors

Shilpa Jain, Maria G. Kapetanaki, Nalini Raghavachari, Kimberly Woodhouse, Guoying Yu, Suchitra Barge, Claudia Coronnello, Panayiotis V. Benos, Gregory J. Kato, Naftali Kaminski, Mark T. Gladwin

Abstract

Increased platelet activation in sickle cell disease (SCD) contributes to a state of hypercoagulability and confers a risk of thromboembolic complications. The role for post-transcriptional regulation of the platelet transcriptome by microRNAs (miRNAs) in SCD has not been previously explored. This is the first study to determine whether platelets from SCD exhibit an altered miRNA expression profile.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 71 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Colombia 1 1%
Canada 1 1%
Brazil 1 1%
Unknown 68 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 11 15%
Researcher 9 13%
Student > Master 8 11%
Student > Bachelor 6 8%
Student > Doctoral Student 5 7%
Other 13 18%
Unknown 19 27%
Readers by discipline Count As %
Agricultural and Biological Sciences 20 28%
Biochemistry, Genetics and Molecular Biology 13 18%
Medicine and Dentistry 10 14%
Engineering 2 3%
Immunology and Microbiology 2 3%
Other 5 7%
Unknown 19 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 October 2013.
All research outputs
#18,952,091
of 24,155,398 outputs
Outputs from PLOS ONE
#160,436
of 207,671 outputs
Outputs of similar age
#147,804
of 202,029 outputs
Outputs of similar age from PLOS ONE
#3,630
of 5,161 outputs
Altmetric has tracked 24,155,398 research outputs across all sources so far. This one is in the 18th percentile – i.e., 18% of other outputs scored the same or lower than it.
So far Altmetric has tracked 207,671 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.6. This one is in the 19th percentile – i.e., 19% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 202,029 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 23rd percentile – i.e., 23% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 5,161 others from the same source and published within six weeks on either side of this one. This one is in the 24th percentile – i.e., 24% of its contemporaries scored the same or lower than it.